[Pathogenesis of immunologic deficiency in the initial stage of lymphogranulomatosis in children].

Antilymphocytic monoclonal antibodies of HKO and OKT series were used to study surface antigens of peripheral blood and lymph node lymphocytes in 13 untreated patients with Hodgkin's disease. The purpose of the study was to identify the pathogenetic mechanism underlying the development of immunodeficiency in the early disease stages. The data obtained have demonstrated that the deficiency of T lymphocytes in the peripheral blood was connected with that of mature T cells in the lymph nodes revealed with the use of differential antigens complex.

[Immunocytological characteristics of primary lesions of the lymph nodes in children with lymphogranulomatosis].

Antilymphocytic monoclonal antibodies of UKO and OKT series were used to study surface lymphocytic antigens in 40 primarily affected lymphatic nodes in 19 children with lymphogranulomatosis. In 17 lymphatic nodes immunological reaction was determined as the T-type (OKT3+--42.3 +/- 2.