Effectiveness of family work interventions on schizophrenia: evidence from a multicentre study in Catalonia.

Background: Despite their proven efficacy, family work interventions on families of patients with schizophrenia are not being implemented in routine clinical practice in contexts where expressed emotion levels among caregivers are relatively high.

Aims: This study aimed to explore the effectiveness of a family work intervention in a Mediterranean environment in Catalonia, Spain.

Method: Participants were 23 patients and 35 key relatives in five different clinical settings.

The WFS1 (Wolfram syndrome 1) is not a major susceptibility gene for the development of psychiatric disorders.

Background: Wolfram syndrome is a neurodegenerative disorder that is inherited in an autosomal recessive mode and characterized by the presence of diabetes mellitus and optic atrophy. Patients and heterozygote carriers are at an increased risk of suffering psychiatric disorders. Mutations in the Wolfram gene (WFS1 ) (4p16.