Cavernous liver hemangioma complicated with spontaneous intratumoral hemorrhage: a case report and literature review.

Hemangiomas, the most common benign tumors of the liver, have a prevalence of approximately 20% and are more frequent in women. According to previous studies, the size and location of the tumor are correlated with the appearance of symptoms and complications. Cases of hemangiomas complicated by spontaneous intratumoral hemorrhage have been rarely reported in the literature.

The evaluation of the sentinel lymph nodes status in breast carcinoma using microscopic, immunohistochemical and cytomorphometric methods in order to establish new stadializations and therapeutic schemes.

The state of axillary lymph nodes represents the most important prognostic parameter in patients with breast carcinoma. The biopsy and examination of sentinel lymph nodes, the former one containing metastases originating in mammary carcinoma, allows a better stadialization of the tumor but also the avoiding of the extirpation of the axilla, associated with a series of complications and high costs of hospitalization. In establishing the tumoral prognosis, not only the diameter but also the localization of the metastasis in the lymph nodes is utterly important.

[Study of nucleolar organizer regions in prostate cancer].

Aim: To compare the qualitative and quantitative AgNOR scores per nucleus of histological grades.

Material And Methods: Thirty-five needle biopsies from patients with prostate cancer (PC) aged 60 to 75 years were investigated. The morphologic parameters examined on histological specimens were: microscopic patterns, Gleason's histological grades (GLG), and AgNOR scores by automated image analyzer and quantitative AgNOR counts according to the classification, fine granules, large granules, and total granule counts.

The endovaginal ultrasound finding of a thin and regular endometrium is uncommon in endometrial cancer.

Aim: To present the clinical and ultrasound features in patients with endometrial cancer in whom the endometrial thickness was less that 5 mm.

Method: Retrospective study on 263 patients with endometrial carcinoma in whom the ultrasound evaluation of the endometrium was performed. The features noticed in the patients with endometrial thickness below 5 mm are presented.

T-cell primary cutaneous lymphomas. A clinicopathological and immunohistochemical study.

Within the large framework of the lymphoproliferative diseases, the primary cutaneous lymphomas are distinct pathologic conditions, defined by particular morphologic, immunologic, genetic, and clinic criteria. The study aimed to create the first clinicopathological and immunohistochemical profile of primary cutaneous lymphoma for a Romanian region. We investigated a series of 16 cases (diagnosed during a 5-year period) in accordance with the general principles of primary cutaneous lymphoma management.

Metastasis from papillary renal cell carcinoma masquerading as primary ovarian clear cell tumor.

A 73-year-old female presented with a left ovarian tumor mass. Microscopic examination disclosed cystic spaces lined by abundant clear and eosinophilic tumor cells with pleomorphic nuclei. Differential diagnosis included primary ovarian oxyphilic-type clear cell carcinoma and sex-cord tumor with extensive luteinization.

[Evaluation of peritoneal extensions for the diagnosis and management of serous ovarian borderline tumors].

Serous borderline tumours of the ovary represent a heterogeneous group of epithelial ovarian neoplasm. They are usually associated with a favourable outcome. Some of them have a worse prognosis.

The value of intraoperative diagnosis in breast lesions.

Unlabelled: Frozen section examination is aimed at making a preoperative diagnosis, determining the benign or malignant nature of a breast lesion, but also the most suitable surgical procedure. The sensitivity and specificity of this method and the causes of discrepancies were analyzed in a retrospective study of 2 177 breast lesions.

Method: 1,150 frozen sections from 2,177 breast lesions were performed in the interval 1999-2005.

[Acinic cell adenocarcinoma of the lip].

The variable histological appearance of acinic cell carcinoma coupled with its uncommon occurrence account for considerable diagnostic difficulties. We present the case of a 68 years old women, with a salivary cyst localised in the upper lip. The tumour mass was excised, fixed in formaline, embedded in paraffin and the sections were stained with Haematoxylin-Eosin, PAS-Haematoxylin, PAS-Alcian blue and Perls.

Adenosquamous cervical carcinoma morphological characteristics.

Adenosquamous carcinomas range between 5-25% of cervical cancers and are composed by an admixture of malignant squamous and glandular elements. The aim of our study was to identify some common characteristics and to evaluate the correlation between the degrees of differentiation of the two components. We analyzed 15 cases diagnosed in a 6 years period.

The morphologic changes induced by hormone and radiation therapy on prostate carcinoma.

The morphologic changes induced by hormone and radiation therapy were evaluated in prostate biopsy and prostatectomy specimens from patients with residual prostate carcinoma. The two therapeutic methods induce changes both in the nonmalignant and malignant residual prostatic tissue. Following hormone therapy, the nonmalignant prostatic tissue showed atrophy of prostatic acini associated with fibrosis, basal cell hyperplasia, degenerative changes of the secretory epithelial cells, and a marked decrease of high-grade intraepithelial neoplasia (HGPIN).

[The significance of intestinal metaplasia related to gastric ulcer].

Purpose: Intestinal metaplasia is considered an intermediary stage of gastric carcinogenesis. Thus, we aim to investigate lesions of intestinal metaplasia diagnosed at patients with peptic ulcer.

Material And Methods: Our study was achieved on a group of 212 patients, clinically diagnosed with gastric ulcer and having partial gastrectomy.

Molecular mechanisms in hormone-resistant prostate cancer.

Prostate cancer is the most common malignancy in males. Despite the efforts for an early diagnosis, approximately one third of the cases are diagnosed in advanced clinical stages. Prostatic cancer, as the function of normal prostate is dependent upon androgens.

[Endosalpingiosis of the axillary lymph nodes--primary or metastatic tumour?].

The involvement of extra-abdominal sites by serous ovarian tumours of low malignant potential is extremely rare. In this paper we present the case of a 33 years old woman, diagnosed with atypical endosalpingiosis in the axillary lymph nodes before the diagnosis of a bilaterally ovarian serous tumour of low malignant potential. The occurrence of axillary lymph nodes involvement associated with serous tumours of the ovary could be explained by the presence of circulating serous cells that remained dormant for a period of time or by the development of an independent primary tumour from glandular inclusions in axillary lymph nodes.

[Hepatic changes due to the administration of midazolam and ketamine--an experimental study].

Unlabelled: The aim of the study was the investigation of the secondary effects at the hepatic level determined by anesthetics.

Material And Methods: There were used 4 groups of 10 mature white Wistar rats, males and females. Group I was the witness group.

[The significance of morphologic and immunohistochemical patterns in the diagnosis of undifferentiated endometrial sarcoma].

We present the case of a 56-year-old woman presenting an uterine tumor associated with pain and vaginal bleeding. The slides from the tumor were studied with monoclonal antibodies to Vimentin, CD 10, KL 1, Actin, Desmin, CD 34, S 100 protein, Ki 67, PCNA. The tumor cells were Vimentin and CD 10 diffuse positive, focal Actin positive, Desmin, KL 1, CD 34 and S 100 protein-negative.