Functional alterations of retinal neurons and vascular involvement progress simultaneously in the Psammomys obesus model of diabetic retinopathy.

To investigate the progression of diabetic retinopathy (DR) in a new diurnal animal model, we monitored clinically the DR in Psammomys obesus (P. obesus) during 7 months using electroretinography (ERG) and imaging techniques. After the onset of DR, all ERG components decreased progressively.

Retinal dysfunction parallels morphologic alterations and precede clinically detectable vascular alterations in Meriones shawi, a model of type 2 diabetes.

Diabetic retinopathy is a major cause of reduced visual acuity and acquired blindness. The aim of this work was to analyze functional and vascular changes in diabetic Meriones shawi (M.sh) an animal model of metabolic syndrome and type 2 diabetes.

Melatonin ingestion after exhaustive late-evening exercise improves sleep quality and quantity, and short-term performances in teenage athletes.

The present study aimed to explore the effects of a single 10-mg dose of melatonin (MEL) administration after exhaustive late-evening exercise on sleep quality and quantity, and short-term physical and cognitive performances in healthy teenagers. Ten male adolescent athletes (mean ± SD, age = 15.4 ± 0.

Electroretinographic evidence suggesting that the type 2 diabetic retinopathy of the sand rat Psammomys obesus is comparable to that of humans.

Purpose: Type 2 diabetic retinopathy is the main cause of acquired blindness in adults. The aim of this work was to examine the retinal function of the sand rat Psammomys obesus as an animal model of diet-induced type 2 diabetes when subjected to a hypercaloric regimen.

Materials And Methods: Hyperglycemia was induced in Psammomys obesus by high caloric diet (4 kcal/g).

Effects of one-night sleep deprivation on selective attention and isometric force in adolescent karate athletes.

Background: Most of the available literature related to aspects of sleep deprivation is primarily focused on memory and learning, and studies regarding its effects on selective attention and/or physical performance are scarce. Moreover, the available literature includes general population or people involved in team sports (e.g.

Characterizing the Retinal Function of Psammomys obesus: A Diurnal Rodent Model to Study Human Retinal Function.

Purpose: To compare the retinal function of a diurnal murid rodent, Psammomys obesus, with that of Wistar albino rat and human subjects.

Materials And Methods: Adult Psammomys obesus were captured and transferred to the animal facilities where they were maintained at 25°C with standard light/dark cycles and natural halophilic plants, rich in water and mineral salts. Standard full-field photopic and scotopic electroretinograms were obtained.

Ramadan fasting does not adversely affect neuromuscular performances and reaction times in trained karate athletes.

Background: The present study aimed to investigate the concomitant effects of Ramadan intermittent fast (RIF) and muscle fatigue on neuromuscular performances and reaction times in young trained athletes.

Methods: Eight karate players (17.2 ± 0.

Cardiac autonomic control in the obstructive sleep apnea.

Introduction: The sympathetic activation is considered to be the main mechanism involved in the development of cardiovascular diseases in obstructive sleep apnea (OSA). The heart rate variability (HRV) analysis represents a non-invasive tool allowing the study of the autonomic nervous system. The impairment of HRV parameters in OSA has been documented.

Improved tolerance of peripheral fatigue by the central nervous system after endurance training.

Purpose: The purposes of this study were to evaluate the effect of endurance training on central fatigue development and recovery.

Methods: A control group was compared to a training group, which followed an 8-week endurance-training program, consisting in low-force concentric and isometric contractions. Before (PRE) and after (POST) the training period, neuromuscular function of the knee extensor (KE) muscles was evaluated before, immediately after and during 33 min after an exhausting submaximal isometric task at 15 % of the maximal voluntary contraction (MVC) force.

Reference values of vertical jumping performances in healthy Tunisian adolescent.

Background: The assessment of normal values of muscle strength can be determined for the health outcome of adolescents, especially those who are living in a developing country.

Aims: The purpose of this study is to identify the relationship between anthropometric variables and vertical jumping performances. The jump height and the average of power were measured to establish reference values of vertical jumping parameters in Tunisian healthy adolescents aged 13-19 in both sexes.

Reducing resistance training volume during Ramadan improves muscle strength and power in football players.

We aimed to examine the effect of maintaining or reducing resistance training volume during Ramadan-intermittent-fasting (RIF) on short-term maximal performances. 20 footballers (age: 18.4 ± 0.

Effects of time-of-day and partial sleep deprivation on short-term maximal performances of judo competitors.

This study assessed the effects of partial sleep deprivation on short-term maximal performances of judokas in the morning and afternoon of the following day. In a randomized design, 12 judokas completed the maximal voluntary contraction, the handgrip, and the Wingate tests before and after a judo combat. Measurements were performed at 09:00 and 16:00 hours after a reference-normal sleep night and 2 conditions of 4-hour partial sleep deprivation timed at the beginning (SDB) or at the end of the night (SDE).

Effects of partial sleep deprivation on proinflammatory cytokines, growth hormone, and steroid hormone concentrations during repeated brief sprint interval exercise.

The purpose of this study was to evaluate the effects of partial sleep deprivation (PSD) on circulating concentrations of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) in relation to the secretory profiles of growth hormone (GH), cortisol, and testosterone during a repeated brief sprint interval exercise. Thirty healthy football players (mean age: 21.1 [range: 18-24] years; body mass index [BMI]: 22.

Time of day effects on repeated sprint ability.

The present study aimed at investigating the effects of time-of-day on muscle power and associated electromyographic (EMG) activity level of 4 thigh muscles during a repeated pedalling sprint exercise. After a familiarization session, 12 male subjects were asked to perform the repeated sprint ability test during 2 experimental sessions (randomized order), which were set up either at 06:00 or 18:00 h. For each sprint, peak power output, percentage of peak power decrement and total work were calculated.

The effect of training at a specific time-of-day on the diurnal variations of short-term exercise performances in 10- to 11-year-old boys.

The aim of this study was to assess the effect of time-of-day-specific training on the diurnal variations of short-term performances in boys. Twenty-four boys were randomized into a morning-training-group (07:00-08:00h; MTG), an evening-training-group (17:00-18:00h; ETG) and a control-group (CG). They performed four tests of strength and power (unilateral isometric maximal voluntary contraction of the knee extensor muscles, Squat-Jump, Counter-Movement-Jump and Wingate tests) at 07:00 and 17:00h just before (T0) and after 6 weeks of resistance training (T1).

The relative contributions of anthropometric variables to vertical jumping ability and leg power in Tunisian children.

The purpose of this study was to examine the relative contributions of anthropometric variables to vertical jumping ability and leg power and to establish reference values of vertical jumping parameters in athletic Tunisian children aged 7-13 years in both sexes. Three hundred and ninety-one athletic Tunisian children (208 boys and 183 girls) aged 7-13 years were randomly selected to participate in our study. They were asked to perform squat jumps and countermovement jumps.

Comparison of recovery strategies on maximal force-generating capacity and electromyographic activity level of the knee extensor muscles.

Context: With regard to intermittent training exercise, the effects of the mode of recovery on subsequent performance are equivocal.

Objective: To compare the effects of 3 types of recovery intervention on peak torque (PT) and electromyographic (EMG) activity of the knee extensor muscles after fatiguing isokinetic intermittent concentric exercise.

Design: Crossover study.

The effect of training at the same time of day and tapering period on the diurnal variation of short exercise performances.

The purpose of this investigation was to assess the effects of training and tapering at the same time of the day on the diurnal variations of short exercise performances. Thirty-one physically active men underwent 12 weeks of lower-extremity resistance training and 2 weeks of tapering. These subjects were matched and randomly assigned to a morning training group (MTG, training times 0700-0800 hours, n = 10), an evening training group (ETG, training times 1700-1800 hours, n = 11), and a control group (CG, completed all tests but did not train, n = 10).

Diurnal variation in Wingate-test performance and associated electromyographic parameters.

The present study was designed to evaluate time-of-day effects on electromyographic (EMG) activity changes during a short-term intense cycling exercise. In a randomized order, 22 male subjects were asked to perform a 30-s Wingate test against a constant braking load of 0.087 kg·kg(-1) body mass during two experimental sessions, which were set up either at 07:00 or 17:00 h.

Time-of-day effects on short-term exercise performances in 10- to 11-year-old boys.

The purpose of this study was to examine the time-of-day effects on short-term performances in boys. In a balanced and randomized study design, 20 boys performed four anaerobic tests of strength and power (grip strength, Squat-Jump, Five-jump and cycle Wingate tests) at 08:00, 14:00 and 18:00 hr on separate days. The results showed a time-of-day effect on oral temperature.

Genetic linkage study of an autosomal recessive form of juvenile myoclonic epilepsy in a consanguineous Tunisian family.

Juvenile myoclonic epilepsy (JME) is the most common idiopathic generalized epilepsies (IGEs), affecting 12-30% of all epilepsies in medical centers. To date genetic linkage studies have revealed putative loci on different chromosomes, but these findings are still inconclusive about which gene precisely is responsible for the disease. Here, we report the genetic and clinical analysis of a (JME) consanguineous Tunisian family with four affected children out of eight.

Changes in EEG activity before and after exhaustive exercise in sedentary women in neutral and hot environments.

This study examined the effect of hyperthermia on brain electrical activity measured with encephalography during prolonged exhaustive exercise in a group of sedentary women (VO(2)max = 35 +/- 4 mL kg min(-1)). Two strenuous cycling exercises were performed either in neutral (N-Ex) or in heat (H-Ex) conditions. Tympanic temperature (Tty), heart rate (HR), body mass loss (BML), plasma volume decrease, and brain electrical activity [EEG: alpha (8-13 Hz) and beta(13-30 Hz)-band and alpha/beta index of fatigue: the ratio between EEG activity in the alpha band and beta-band] were recorded throughout the cycling sessions.

Dimorphism of TAP-1 gene in Caucasian with juvenile myoclonic epilepsy and in Tunisian with idiopathic generalized epilepsies.

Juvenile myoclonic epilepsy (JME) is the most common form of idiopathic generalized epilepsies (IGE) that account for about 5-10% of all types of epilepsies. The first putative locus termed EJM1 is on the human leucocyte antigen (HLA-II) region of chromosome 6p21.3.