Phytochemical screening of an essential oil-loaded PVA/GA hydrogel membrane for potential wound healing application.

The global concern over microbial resistance, particularly the emergence of antibiotic resistance, underscores the imperative for novel antimicrobial strategies. Plant essential oils and biopolymers offer promising alternatives to conventional drugs for bacterial and fungal infections. The objective was to achieve optimized antibacterial activity and to identify the phytochemical component of the essential oil.

Optimizing the thermophysical behavior of a novel ternary hybrid nanofluid for energy applications through experimental research.

The continual use of fossil fuel technologies has negatively impacted on the environment and has caused huge health challenges globally. Despite the growth of renewable energy technologies, their efficiency issues have hindered widespread adoption. The use of nanofluids as heat transfer fluids in renewable energy technologies have further improved their overall efficiency, resulting in a more environmentally friendly performance of these systems.

Investigation of composition, antioxidant, antimicrobial and cytotoxic characteristics from Juniperus sabina and Ferula communis extracts.

Plants have been one the most valuable sources of biologically active compounds. This study investigates the chemical composition, as well as the antioxidant, antimicrobial, and cytotoxic activities of methanolic and ethanolic extracts from Juniperus sabina and Ferula communis leaves, grown in Cyprus. Total phenolic and flavonoids content of methanol and ethanol extracts were quantified.

Role of energy consumption and trade openness towards environmental sustainability in Turkey.

The growth of financial services has been critical in Turkey's pursuit of economic growth objectives throughout the last two decades. Nevertheless, it cannot be denied that it has a negative impact on environmental quality. Based on this, in the current paper, the effect of energy use, trade openness, and financial development on the load capacity factor (LCF) is explored for Turkey between 1965 and 2018.

Biogenic Synthesis and Characterization of Chitosan-CuO Nanocomposite and Evaluation of Antibacterial Activity against Gram-Positive and -Negative Bacteria.

Chitosan-copper oxide (CHT-CuO) nanocomposite was synthesized using olive leaf extract (OLE) as reducing agent and CuSO4⋅5H2O as precursor. CHT-CuO nanocomposite was prepared using an in situ method in which OLE was added to a solution of chitosan and CuSO4⋅5H2O mixture in the ratio of 1:5 (v/v) and heated at a temperature of 90 °C. The obtained CHT-CuO nanocomposite was characterized using field emission scanning electron microscopy (FE-SEM), X-ray diffraction (XRD), ultraviolet-visible (UV-Vis) spectrophotometry, energy-dispersive X-ray spectroscopy (EDAX), Fourier transform infrared spectroscopy (FTIR), and high-resolution transmission electron microscopy (TEM).

Freeze-dried crosslinked anionic hydrogels composed of poly(vinyl pyrrolidone) and poly(vinyl alcohol): synthesis, characterization and degradability performance.

Purpose: Poly(vinyl pyrrolidone) (PVP) and poly(vinyl alcohol) (PVA) has enticed significant research interest and are acknowledged among the principal volume of synthetic polymers that have been fabricated globally for nearly one century. This is as a result of their excellent attributes which dictated its wide-ranging usage in a range of applications, chiefly in medical field. The investigation is aimed at preparing PVP/PVA hydrogels using freeze drying technique for its characterization and accessing the biodegradability of the prepared hydrogel.

An evaluative investigation of the delivery of cytarabine with RGD decorated solid lipid nanoparticles.

Aim: To synthesise cytarabine-loaded SLNs modified with the RGD peptide as a ligand, suitable for effective cancer therapy.

Methods: SLNs were synthesised by the high shear, hot homogenisation technique. A 2 level 3 factor analysis was used in optimisation.

Mechanisms of Drug Resistance and Use of Nanoparticle Delivery to Overcome Resistance in Breast Cancers.

Breast cancer is the leading cancer type diagnosed among women in the world. Unfortunately, drug resistance to current breast cancer chemotherapeutics remains the main challenge for a higher survival rate. The recent progress in the nanoparticle platforms and distinct features of nanoparticles that enhance the efficacy of therapeutic agents, such as improved delivery efficacy, increased intracellular cytotoxicity, and reduced side effects, hold great promise to overcome the observed drug resistance.

Biosynthesized ZnO Nanoparticles Using Extract Induced Biochemical and Morphological Alterations in Wistar Rats.

Nano-based particles synthesized via green routes have a particular structure that is useful in biomedical applications as they provide cheap, eco-friendly, and non-toxic nanoparticles. In the present study, we reported the effect of various concentrations of Zinc oxide nanoparticles synthesized using stem bark extract (ZnO NPsAL) as stabilizing agent on rat biochemical profiles and tissue morphology. Adult Wistar rats weighing 170 ± 5 g were randomly classified into eight groups of five rats each; Group A served as a control fed with normal diet and water.

Effect of extraction temperature and solvent type on the bioactive potential of Ocimum gratissimum L. extracts.

Ocimum gratissimum is a shrub that belongs to the Lamiaceae family of plants. Despite the known biological activities and ethnomedicinal applications, comparative evaluation of the effects of different extraction techniques on the chemical and bioactive properties of O. gratissimum extracts has not yet been performed.

Chitosan And N, N, N-Trimethyl Chitosan Nanoparticle Encapsulation Of Essential Oil: Optimised Synthesis, In Vitro Release And Bioactivity.

Background: The encapsulation of plant essential oils (EOs) with polymeric materials (e.g. chitosan (CS) and N, N, N-trimethyl chitosan (TMC)) and the further reduction of the polymers into their nano sizes are gaining research interest in nanotechnology due to potential applications in medical drug delivery systems as well as the food and pharmaceutical industry.

Effective and reusable nano-silica synthesized from barley and wheat grass for the removal of nickel from agricultural wastewater.

In the present study, a comparative analysis was performed on the extraction of nickel ions (Ni) from agricultural wastewater using nanosilica (NS) synthesized from barley (NS-B) and wheat (NS-W) grass waste with a yield of 92.4%. The experimental procedure was conducted on barley and wheat waste to obtain an 85% pure NS that served as the adsorbent for nickel extraction in wastewater.

Synthesis, characterization, antimicrobial and antimetastatic activity of silver nanoparticles synthesized from Ficus ingens leaf.

Cancer incidence is still increasing due to inadequate responsive treatments. Inertness and biocompatibility of nanoparticles synthesized using plant extracts have shown therapeutic applications and make it to be a good anti-cancer candidates. This study is a recent novel spotlight that synthesized silver nanoparticle from Ficus ingens leaf extract (FILE) and studied its anti-metastatic and anti-bacterial activity.

Biosynthesis of zinc oxide nanoparticles using stem bark, and evaluation of its antimicrobial, antioxidant, and cytotoxic activities on human breast cancer cell lines.

Background: Biocompatibility and stability of zinc oxide nanoparticles (ZnO NPs) synthesized using plants is an interesting research area of study in nanotechnology, due to its wide applications in biomedical, industrial, cell imaging, and biosensor fields. The present study reports the novel green synthesis of stable ZnO NPs using various concentrations of zinc nitrate (0.01M, 0.

Physiochemical characterization, antioxidative, anticancer cells proliferation and food pathogens antibacterial activity of chitosan nanoparticles loaded with Cyperus articulatus rhizome essential oils.

Essential oil of Cyperus articulatus have known bioactivities, the qualitative chemical composition analysis of the Essential Oils (EOs) by Gas Chromatography-Mass Spectrometry (GC-MS) revealed the presence of new compounds not previously known to the plant rhizome which includes, sesquiterpenes, monoterpenes, nootkatone, 6-methyl-3,5-heptadien-2-one, retinene, nopinone, cycloeucalenol, anozol, toosendanin, furanone, ethanone and vitamin A. Cyperus articulatus Essential Oils (CPEOs) loaded Chitosan Nanoparticles (CSNPs) was successful synthesized using an oil-in-water mixture and ionic gelation method and were characterized by Scanning Electron Microscopy (SEM), Fourier Transform Infrared Spectroscopy (FTIR) and UV-Vis spectrophotometry. CPEOs had more radical-scavenging bioactivity in vitro than CSNPs and CPEO-CSNPs at initial storage times.

Comparison of protein- and polysaccharide-based nanoparticles for cancer therapy: synthesis, characterization, drug release, and interaction with a breast cancer cell line.

In this study, human serum albumin (HSA) was used as a protein-based material and poly (3-hydroxybutyrate) (PHB)-carboxymethyl chitosan (CMCh) as a polysaccharide-based material for the production of nanoparticles to be used as nanocarriers in cancer therapy. HSA and PHB-CMCh nanoparticles were prepared and characterized with a Zeta Sizer, Fourier transform infrared spectroscopy, scanning electron microscopy, and atomic force microscope. The effects of the pH value of the suspending medium and the amounts of crosslinker and polymer concentration on nanoparticle size and size distribution were investigated.

Emerging technologies for assembly of microscale hydrogels.

Assembly of cell encapsulating building blocks (i.e., microscale hydrogels) has significant applications in areas including regenerative medicine, tissue engineering, and cell-based in vitro assays for pharmaceutical research and drug discovery.

Preparation and characterization of magnetically responsive bacterial polyester based nanospheres for cancer therapy.

Polyhydroxyalkanoates (PHA) are natural, thermoplastic polyesters and due to their biocompatible and biodegradable properties they are good alternatives for the production of scaffolds for engineered tissues or nanoparticles for drug delivery. As a member of polyhydroxyalkanoate family, polyhydroxybutyrates (PHB) have been widely used as a biomaterial for in vitro and in vivo studies since their mechanical properties are very similar to conventional plastics. By using multi-emulsion technique, iron oxide particles were coated with polyhydroxybutyrate (PHB) polymer synthesized from Alcaligenes eutrophus bacteria and the magnetic carrier system was prepared accordingly.

Release of magnetic nanoparticles from cell-encapsulating biodegradable nanobiomaterials.

The future of tissue engineering requires development of intelligent biomaterials using nanoparticles. Magnetic nanoparticles (MNPs) have several applications in biology and medicine; one example is Food and Drug Administration (FDA)-approved contrast agents in magnetic resonance imaging. Recently, MNPs have been encapsulated within cell-encapsulating hydrogels to create novel nanobiomaterials (i.