Fertility, pregnancy outcomes, and disease activity during pregnancy in patients with juvenile idiopathic arthritis: a descriptive study.

To investigate the fertility status, pregnancy outcomes, and disease activity during and after pregnancy in patients with juvenile idiopathic arthritis (JIA) currently being followed up at an adult rheumatology clinic. This study included 141 adult patients diagnosed with according to the International League of Associations for Rheumatology criteria, who are now monitored at an adult rheumatology clinic. Data on demographics, disease characteristics, medication history, fertility status, and pregnancy outcomes were collected through medical records and patient interviews.

Electrolytic Ni-P and Ni-P-Cu Coatings on PCM-Loaded Expanded Graphite for Enhanced Battery Thermal Management with Mechanical Properties.

This study addresses the thermal management challenge in battery systems by enhancing phase change material composites with Ni-P and Ni-P-Cu coatings on phase change material/expanded graphite structures. Traditional phase change materials are limited by low thermal conductivity and mechanical stability, which restricts their effectiveness in high-demand applications. Unlike previous studies, this work integrates Ni-P and Ni-P-Cu coatings to significantly improve both the thermal conductivity and mechanical strength of phase change material/expanded graphite composites, filling a crucial gap in battery thermal management solutions.

Could Maladaptive Daydreaming Delay ADHD Diagnosis Until Adulthood? Clinical Characteristics of Adults With ADHD Based on Diagnosis Age.

Introduction: Our study aimed to compare the sociodemographic, diagnostic, clinical, and self-report scale data of adults diagnosed with ADHD in childhood/adolescence versus adulthood and to identify risk factors associated with delayed/missed diagnosis for ADHD.

Method: Sociodemographic, clinical, and diagnostic data of 214 adults with ADHD, followed at the Adult Neurodevelopmental Disorders Clinic, Selçuk University, between January 2022 and January 2024, were analyzed. The diagnostic evaluations were made using the Structured Clinical Interview for DSM-5 Clinician Version.

Blood Cytokine Profile in Breast Cancer: Focusing on Differences among Molecular Subtypes.

Background: Breast cancer is the leading cause of cancer-related deaths in women. Cytokines have been linked to various cancers, and both benign and malignant breast diseases are associated with inflammation. However, there is limited understanding of how the immune system's cytokine response varies among different subtypes of breast cancer.

Assessment of sinapic acid's protective effects against ethanol-induced gastric ulcers in rats.

This study evaluates the protective effects of sinapic acid (SA), a polyphenolic compound with diverse biological activities, against ethanol-induced gastric ulcers in rats. A gastric ulcer model was established using ethanol (ETH), and the experimental groups received either omeprazole (OMEP, 20 mg/kg) or SA at doses of 20 mg/kg and 40 mg/kg via oral gavage for 14 days. Biochemical markers, including total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), malondialdehyde (MDA), and myeloperoxidase (MPO) activity, were assessed alongside proinflammatory cytokines (tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), and IL-6) using ELISA.

Effectiveness of static, dynamic and combined dry needling techniques in the management of myofascial pain syndrome: A three-group study.

Objectives: This study aims to evaluate and compare the therapeutic effectiveness of static dry needling (S-DN), dynamic dry needling (D-DN), and a combined technique (CT) for managing myofascial pain syndrome (MPS).

Patients And Methods: Between January 1, 2023 and April 15, 2023, a total of 38 patients (9 males, 29 females; mean age: 40.5±12.

Tumor mutational burden as a marker for radiologic response to immune checkpoint inhibitors.

Purpose: This study aimed to evaluate the utility of tumor mutational burden (TMB) as a marker for radiologic response to immune checkpoint inhibitor (ICI) therapy at a single tertiary cancer center.

Materials And Methods: In this retrospective study, out of 1044 patients treated with ICIs between January 2010 and November 2018, 75 patients (38 males and 37 females) with a mean age of 62 (range 22-87) years, who had information about TMB and adequate imaging, were included. Imaging response was determined according to iRECIST criteria.

Effect of type of delivery and anesthesia method to ABR results on newborn hearing screening.

Objectives: The aim of this study is to examine the effect of type of delivery and anesthesia method on the screening ABR test results of newborns within the scope of the Newborn Hearing Screening Program (NHCP) and to investigate the relationship between the test results and the relevant variables.

Methods: 441 newborns were included in the study. Of these newborns, 221 constituted the control group (normal (vaginal) delivery), and 220 constituted the study group (cesarean section, delivery).

A novel approach to antimicrobial resistance: Machine learning predictions for carbapenem-resistant Klebsiella in intensive care units.

This study was conducted at Kocaeli University Hospital in Turkey and aimed to predict carbapenem-resistant Klebsiella pneumoniae infection in intensive care units using the Extreme Gradient Boosting (XGBoost) algorithm, a form of artificial intelligence. This was a retrospective case-control study involving 289 patients, including 159 carbapenem-resistant and 130 carbapenem-susceptible individuals as controls. The model's predictive analysis combined a diverse range of demographic, clinical, and laboratory data, resulting in an average accuracy of 83.

Molecular connectomics reveals a glucagon-like peptide 1-sensitive neural circuit for satiety.

Liraglutide and other glucagon-like peptide 1 receptor agonists (GLP-1RAs) are effective weight loss drugs, but how they suppress appetite remains unclear. One potential mechanism is by activating neurons that inhibit the hunger-promoting Agouti-related peptide (AgRP) neurons of the arcuate hypothalamus (Arc). To identify these afferents, we developed a method combining rabies-based connectomics with single-nucleus transcriptomics.

The Investigation of the Relationship Between Mortality Awareness and Spiritual Care Competencies of Nurses Working in Intensive Care and Palliative Care Units.

The aim of this study was to investigate the relationship between mortality awareness and spiritual care competence among nurses working in intensive care and palliative care units. This cross-sectional, descriptive and correlational study included a sample of 163 nurses who had worked for at least one month in intensive care and palliative care units in two hospitals. Data were collected between 02/01/2024 and 28/06/2024.

Retrospective analysis of hemophilia B in Turkey: identifying main characteristics and treatment options.

Background: Hemophilia B (HB), an X-linked recessive inherited bleeding disorder, exhibits a high prevalence among males.

Objectives: To present the first national cohort of persons with HB to define the demographics, clinical characteristics, and treatment patterns in Turkey.

Methods: This multicenter, retrospective study included 433 alive persons with HB registered in 35 centers between 1961 and 2018.

Search for Soft Unclustered Energy Patterns in Proton-Proton Collisions at 13 TeV.

The first search for soft unclustered energy patterns (SUEPs) is performed using an integrated luminosity of 138  fb^{-1} of proton-proton collision data at sqrt[s]=13  TeV, collected in 2016-2018 by the CMS detector at the LHC. Such SUEPs are predicted by hidden valley models with a new, confining force with a large 't Hooft coupling. In events with boosted topologies, selected by high-threshold hadronic triggers, the multiplicity and sphericity of clustered tracks are used to reject the background from standard model quantum chromodynamics.

Waste refractory brick material added chitosan/oxidized pullulan complex gel production and removal of heavy metals from waste water.

Wastewater is a by-product of numerous industrial processes that have been demonstrated to have adverse effects on human and natural health due to the pollutants it contains. The pollutants in these substances are organic or inorganic molecules and heavy metal ions that significantly harm the environment and human health. A variety of techniques have been devised for the removal of heavy metal ions from wastewater.

Search for the Z Boson Decay to ττμμ in Proton-Proton Collisions at sqrt[s]=13 TeV.

The first search for the Z boson decay to ττμμ at the CERN LHC is presented, based on data collected by the CMS experiment at the LHC in proton-proton collisions at a center-of-mass energy of 13 TeV and corresponding to an integrated luminosity of 138  fb^{-1}. The data are compatible with the predicted background. For the first time, an upper limit at the 95% confidence level of 6.

A Metric Shedding Light on the Relationship Between White Coat Hypertension and Anxiety: The Hospital Anxiety and Depression Scale-Anxiety.

Background: To investigate the relationship between anxiety and white coat hypertension (WCH) using the hospital anxiety and depression scale-anxiety (HADS-A) score.

Methods: Participants lacking a pre-existing diagnosis of hypertension but displaying increased office blood pressure were included in this study. Subsequently, they were classified as either newly diagnosed sustained hypertension (SustHT) or white coat hypertension (WCH) patients, as determined by 24-hour ambulatory blood pressure monitoring measurements.

Synergistic Effects of Polypropylene Fibers and Silica Fume on Structural Lightweight Concrete: Analysis of Workability, Thermal Conductivity, and Strength Properties.

Structural lightweight concrete (SLWC) is crucial for reducing building weight, reducing structural loads, and enhancing energy efficiency through lower thermal conductivity. This study explores the effects of incorporating silica fume (SF), micro-polypropylene (micro-PP), and macro-PP fibers on the workability, thermal properties, and strength of SLWC. SF was added to all mixtures, substituting 10% of the Portland cement (PC), except for the control mixture.

A Polyimide Composite-Based Electromagnetic Cantilever Structure for Smart Grid Current Sensing.

Polyimides (PIs) have been extensively used in thin film and micro-electromechanical system (MEMS) processes based on their excellent thermal and mechanical stability and high glass transition temperature. This research explores the development of a novel multilayer and multifunctional polymer composite electro-piezomagnetic device that can function as an energy harvester or sensor for current-carrying wires or magnetic field sensing. The devices consist of four layers of composite materials with a polyimide matrix.