[The scientific, organizational and methodological bases for the epidemiological surveillance of streptococcal group A infection in a large city].

These investigations have made it possible to establish the extent and scale of the spread of streptococcal infection (group A) and its socioeconomic importance in Moscow, a great mega-police of the world. The deterioration of the epidemiological situation in recent years, accompanied by an increase in morbidity and mortality caused by streptococcal infection, has been demonstrated. The program and conceptual foundations of epidemiological surveillance on this infection in Moscow are presented.

[The role of oxytocin in realizing hypothalamic effects on the motor function of the digestive tract].

Chronic experiments in dogs showed that, after i.v. injection of oxytocin, the latency of activation of gastrointestinal motility by the stimulation of median hypothalamic structures was increased and inhibitory effects of posterior hypothalamic structures on the contractile activity of the digestive tract were intensified.

[The role of adrenergic receptors in the realization of hypothalamic effects on the motor function of the digestive tract in hypophysectomized dogs].

Chronic experiments on hypophysectomized dogs with gastric and small intestinal fistulas as well as with hypothalamus-implanted electrodes have shown that blockade of alfa-adrenoreceptors by phentolamine increases the number of the excitatory motility responses while stimulating hypothalamic structures during rest of the gastrointestinal tract and decreases inhibitory effects of the stomach while stimulating hypothalamic structures during work of the digestive tract. The blockade of beta-adrenoreceptors by obsidan induces weakening of excitatory responses of the digestive tract and intensification of inhibitory ones while stimulating hypothalamic structures in hypophysectomized dogs.

[Interrelations between the hypothalamus and the amygdaloid complex in the regulation of motor function of the digestive tract].

In chronic experiments on dogs, preliminary stimulation of corticomedial and parvocellular basal nuclei of amygdala augmented the motor responses of the gastro-intestinal tract to subsequent stimulation of median hypothalamic structures and weakened the inhibitory effects of posterior hypothalamic structures on motility of the digestive tract. After preliminary stimulation of the hypothalamus, the motor responses of stomach and small intestine to subsequent stimulation of corticomedial and parvocellular basal nuclei of amygdala were enhanced. The data obtained suggest existence of a complex functional hypothalamo-amygdaloid interaction, the hypothalamus with its basic mechanisms of regulation of motor function of the digestive tract playing the leading part in this interaction.

[Additional phonocardiographic symptom and the functional state of the heart during mitral valve prolapse in children].

A review of the clinical pattern and heart function in 50 children (aged 6 to 15 years) with mitral valve prolapse (MVP) demonstrated that MVP was mild or of medium severity and had a favourable course in most of the cases. Systolic extratone due to MVP can be manifested to the greatest degree within the low-frequency range of phonocardiograms. Morphometric and functional electrocardiographic parameters were within the normal range in most of the children.