A Case of Recurrent Myocarditis After COVID-19 Vaccination, Due to Acute Myeloid Leukemia.

A 25-year-old man presented with chest pain and an elevated troponin level following COVID-19 vaccination. Despite initial response to nonsteroidal anti-inflammatory drugs, he developed a recurrent and relapsing course requiring multiple readmissions. Cardiac magnetic resonance imaging confirmed myocarditis.

The educational needs of Canadian homeless shelter workers related to traumatic brain injury.

Background: Traumatic brain injury (TBI) has a higher prevalence in the homeless population. Caregivers to individuals who have TBIs may require better education surrounding screening, diagnosis and management of this disease to tailor interventions to their clients' needs.

Objective: To assess the insight and educational needs of homeless care providers in recognizing and dealing with clients who had experienced a TBI.

Evidence for a novel P2X purinoceptor in human placental chorionic surface arteries.

To characterize the P2x purinoceptor of arteries of human term placenta, a non-innervated organ, actions of ATP, alpha, beta-methylene-ATP and UTP on de-endothelialized chorionic surface artery segments were compared. ATP and alpha,beta-methylene-ATP caused reversible concentration-dependent contractions, but UTP elicited little or no contraction up to 517 microM. Concentration-effect curves to ATP and alpha,beta-methylene-ATP were parallel, and alpha,beta-methylene-ATP, EC50 4.

Slit-ventricle syndrome in shunt operated children.

Chronic intracranial hypotension is considered as a frequent complication in shunted hydrocephalus, besides obstruction and shunt-infections. In the last twenty years 32 cases of slit-ventricle were diagnosed among the more than one thousand operations on hydrocephalic children at the Paediatric Department of the National Institute of Neurosurgery, Budapest, Hungary. Most of them have been operated on in infancy.

Pathological and experimental investigations in a case of gigantism.

A pituitary adenoma was transsphenoidally removed from a 4.5-year-old girl suffering from gigantism. Prior to the operation both the growth hormone (GH) and the prolactin (PRL) levels in the serum were elevated.

Bombesin-induced pancreatic secretion and growth in rats: effect of proglumide, spantide and ranitidine.

The effect of proglumide (400 mg/kg), spantide (400 g/kg) and ranitidine (20 mg/kg) on pancreatic secretory and trophic response to bombesin (10 micrograms/kg) was studied in the rat. Drugs were administered alone or combined with bombesin three times daily for 5 days. Saline-treated rats were used as controls.

Time-specific development of pancreatic hypersecretory capacity during chronic caerulein treatment in rats.

It is well established that repeated injections of the cholecystokinin (CCK) analogue caerulein induce pancreatic hypersecretion and growth, but so far the time-specific development of hypersecretory capacity has not been studied. Rats were given intraperitoneal injections of caerulein (1 microgram/kg) three times daily for 0-7 days. On the day after the last injection a secretory test was performed with the rats under urethane anaesthesia.

Caerulein stimulates pancreatic secretory response in conscious newborn rats.

Unlabelled: The aim of our study was to measure age-dependent, caerulein-stimulated pancreatic enzyme secretion of conscious CFY suckling rats without pancreatic duct cannulation. Pancreatic secretory response was expressed as the decrease in specific enzyme (trypsin, amylase) activity compared to saline-injected control. The study was performed in three phases.

Effect of a new potent CCK antagonist, lorglumide, on caerulein- and bombesin-induced pancreatic secretion and growth in the rat.

1. The effect of lorglumide, a new potent cholecystokinin (CCK) antagonist, on pancreatic secretion and growth induced by caerulein and bombesin was studied in the rat. 2.

Effect of treatment with submaximal and excessive doses of caerulein on pancreatic growth in newborn rats.

Different groups of CFY female newborn rats were treated with saline, or 1 microgram/kg or 100 micrograms/kg doses of caerulein given s. c. 3 x/day.

Caerulein-induced desensitization of enzyme secretion fails in neonatal rat pancreas.

Pancreatic segments of 1-, 3-, 5-, 10-day-old and adult female OFA (Sprague-Dowley strain) rats were superfused with graded concentrations of caerulein (10(-12)-10(-7) M) to establish concentration-response relation of amylase release. Furthermore, pancreatic segments of 3-, 5-, 10-day-old and adult rats were superfused with 10(-10) or 10(-8) M caerulein and then superfusion was repeated with 10(-10) M concentration of caerulein to show whether the phenomenon of desensitization of amylase release can be induced in the postnatal period. The 1-day-old pancreas was found practically insensitive to caerulein.

Effect of bombesin and its mammalian counterpart, GRP, on exocrine pancreas in the rat.

The effect of equimolar doses (6 nmol/kg) of bombesin and its mammalian counterpart, GRP, on pancreatic growth and secretion was studied in adult rats. Both peptides were administered intraperitoneally three times a day for 5 consecutive days. Saline-treated rats were used as controls.

Excessive doses of cerulein stimulate pancreatic growth in suckling rats but damage the pancreas of weaned rats.

The cerulein-stimulated pancreatic growth response was evaluated in 4- and 11-day-old female suckling CFY rats and compared with the pancreatic response of cerulein-treated 24-day-old weaned rats. Cerulein was given subcutaneously in saline in 1-, 10- and 100-micrograms/kg doses t.i.

Caerulein stimulates pancreatic growth and somatic growth in suckling rats.

This study deals with the stimulatory effect of caerulein on pancreatic and somatic growth in CFY suckling rats before weaning. After birth, caerulein (0.25, 0.

Bombesin promotes pancreatic growth in suckling rats.

Unlabelled: The pancreatic growth promoting effect of long term administration of bombesin was investigated in suckling rats. The authors showed that bombesin given in 10 micrograms/kg b.wt doses s.

Immuno-, neuro-, and general toxicologic animal studies on a synthetic pyrethroid: cypermethrin.

The toxicologic properties of the synthetic pyrethroid insecticide cypermethrin have been studied in animal experiments. In the course of acute and subchronic experiments performed by the administration of 1/2 and 1/40, 1/20, and 1/10 proportions of the oral LD50 value, no considerable changes were found in the general toxicologic tests. The compound known to affect the central nervous system, however, induced only a mild enhancement of the central excitation level shown by the EEG investigations in the doses applied.

A rare case of infantile meningioma.

This paper reports the use of ultrasound and computed tomography in combination to diagnose a case of meningioma in a 3-month-old infant, and also describes the treatment.

Immunotoxicological investigation of the effects of a pesticide; cypermethrin.

The effects of a synthetic pyrethroid pesticide cypermethrin on the immune system were studied. The effect of a daily oral administration of 1/40, 1/20 and 1/10 of LD50 was studied in rabbits for its influence on the humoral immune response after vaccination with Salmonella typhi, as well as on cell-mediated immunity. The two higher doses induced a significant dose-dependent decrease of serum antibody titers.

Binding of lincomycin to immunoglobulins has no effect on their antigen-binding capacity.

The interaction of lincomycin and immunoglobulins was examined in vitro. While lincomycin bound to the immunoglobulin molecules seemed to decrease the quantity of IgG and IgM detected by radial immunodiffusion and microzone electrophoresis, the level of specific antibodies could not be demonstrated by enzyme-linked immunosorbent assay (ELISA).