The theoretical basis of this work is the development of autosensitization in exposure to ionizing radiation and well-known desensitizing action of sulphuric agents. To reduce clinical manifestations of a reaction to combined radiotherapy 34 women with diagnosis of cervical cancer (stages I and II) were given 0.5-1 g of purified sulphur mixed with 0.
View Article and Find Full Text PDFIt has been demonstrated in experiments on 2160 CBA mice and mice of mixed breed, irradiated by LD90/30, that therapeutical administration (subcutaneous or intraperitoneal) of immunoglobulins - homologous (polyglobulin, IgG, IgM) or heterologous - polyglobulin, IgG (from human, equine, canine blood) repeated three times, i.e., 2, 24 and 48 hours after irradiation, not only induces longer survival, but also shows a normalizing effect on the commonly developing dysbacteriosis and increased amount of intestinal microflora and, in addition, leads to suppression of postirradiation endogenous infection.
View Article and Find Full Text PDFIzv Akad Nauk SSSR Biol
September 1985
The therapeutic application of native and in vitro exposed (20000 Gy immunoglobulins of horse blood serum increased the survival of irradiated (LD75-95) animals, normalized the quantitative and qualitative status of the small intestine microflora and prevented enterobacteria from penetrating the internal organs. The irradiated preparations were more active than native ones.
View Article and Find Full Text PDFIn studying the plasmocyte reactions in the regional lymph nodes of intact and irradiated mice immunized with native and irradiated globulin it was established that the preparation exposed to 60Co-gamma-rays exhibited an increased capacity of activating the plasma cell proliferation.
View Article and Find Full Text PDFZh Mikrobiol Epidemiol Immunobiol
July 1975
Experiments were conducted on 220 female mice weighing 20--24 g, with the use of 3 types of antigens (sheep erythrocytes, vaccines from the intestinal and paratyphoid bacilli). There proved to be an increase on the 7th and the 14th day of the formation of specific antibodies under the effect of subcutaneous injection of a homologous blood (0.1--0.
View Article and Find Full Text PDFZh Mikrobiol Epidemiol Immunobiol
September 1969