Background: Candida species have emerged as a significant cause of opportunistic infections. Alongside the expression of various virulence factors, the rise of antifungal resistance among Candida species presents a considerable clinical challenge.
Aim: This study aimed to identify different Candida species isolated from clinical specimens, evaluate their antifungal sensitivity patterns, identify key genes regulating virulence mechanisms using multiplex PCR and to assess any correlation between their virulence profiles and antifungal resistance patterns.
Introduction: Quantum cloning operation, started with no-go theorem which proved that there is no capability to perform a cloning operation on an unknown quantum state, however, a number of trials proved that we can make approximate quantum state cloning that is still with some errors.
Objectives: To the best of our knowledge, this paper is the first of its kind to attempt using meta-heuristic algorithm such as Adaptive Guided Differential Evolution (AGDE), to tackle the problem of quantum cloning circuit parameters to enhance the cloning fidelity.
Methods: To investigate the effectiveness of the AGDE, the extensive experiments have demonstrated that the AGDE can achieve outstanding performance compared to other well-known meta-heuristics including; Enhanced LSHADE-SPACMA Algorithm (ELSHADE-SPACMA), Enhanced Differential Evolution algorithm with novel control parameter adaptation (PaDE), Improved Multi-operator Differential Evolution Algorithm (IMODE), Parameters with adaptive learning mechanism (PALM), QUasi-Affine TRansformation Evolutionary algorithm (QUATRE), Particle Swarm Optimization (PSO), Gravitational Search Algorithm (GSA), Cuckoo Search (CS), Bat-inspired Algorithm (BA), Grey Wolf Optimizer (GWO), and Whale Optimization Algorithm (WOA).