Publications by authors named "Doaa Elzaeem Ismail"
Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Predictor for Sepsis Mortality in Children Admitted to Pediatric Intensive Care Unit (PICU): A Comparison With Prothrombin Time/International Normalized Ratio (PT/INR) and Urea/Creatinine Ratio.
Marwa Ibrahem Abdelrazic Gehan Lotfy Abdel Hakeem Mina Sobhy Hanna Omima M Mohamed Doaa Elzaeem Ismail
Cureus
October 2024
Background Sepsis is the primary cause of death in children, and it is crucial to identify patients at high risk of mortality early on in order to provide intensive monitoring and management in the Pediatric Intensive Care Unit (PICU). Objective The objective of this study was to assess the predictive value of routinely used sepsis indicators, including neutrophil gelatinase-associated lipocalin (NGAL), urea to creatinine ratio (urea/Cr), and prothrombin time and international normalized ratio (PT/INR), in predicting death in critically unwell children. Patients and methods A total of 75 children were included in the research conducted at the PICU of Minia University.
View Article and Find Full Text PDFArticle Synopsis
- - The study investigates the alarming rise of carbapenem resistance in *Pseudomonas aeruginosa*, focusing on the presence of class 1, 2, and 3 integrons that can transmit resistance genes.
- - Out of 97 clinical isolates tested, a significant 58.8% were resistant to imipenem, and 86% of the carbapenem-resistant strains harbored carbapenemase genes, indicating strong resistance.
- - The findings highlight that class 1 integrons are prevalent in these resistant strains, underscoring their role in facilitating the spread of antibiotic resistance among *P. aeruginosa* isolates.