The potential Association of Bisphenol A exposure and type 1 diabetes mellitus among Dakahlia Governorate's children sample, Egypt.

Background: Bisphenol A (BPA) is an endocrine disrupter affecting glucose homeostasis.

Objectives: This study aimed to investigate BPA's relationship with Type 1 Diabetes Mellitus (T1DM) in Dakahlia Governorate's children, in Egypt.

Subjects Materials And Methods: The study had two parts: clinical and experimental.

Assessment of reproductive toxicity of gold nanoparticles and its reversibility in male albino rats.

Unlabelled: Nanotechnology has become a trending area in science all over the world. Although gold nanoparticles (AuNPs) have been utilized widely in biomedical fields, potential toxicities may arise from their interactions with biological systems. The current study aimed at evaluating the toxic effects of AuNPs on the reproductive system of adult male albino rats and assessing the recovery probability.

Assessment of genotoxicity of silver nanoparticles on lymphocyte cells of albino rats using comet assay.

Silver nanoparticles, "AgNPs", represent a prominent nanoproduct, but most of the previous toxicity studies on its genotoxicity are still limited. The current study aimed to assess the genotoxicity of AgNPs on lymphocyte cells using comet assay and to study the recovery probability. It was conducted on 50 adult male albino rats divided into "Control group", 10 rats were injected intraperitoneal, "IP", with distilled water for 28 days, and "Test groups", 40 rats were injected "IP" with 13 ± 3 nm AgNPs for 28 days, subdivided into group I: 10 rats were injected with 2 mg/kg AgNPs, group Ia: 10 rats were injected with 2 mg/kg AgNPs and left for another 4 weeks without scarification, group II: 10 rats were injected with 4 mg/kg AgNPs, and group IIa: 10 rats were injected with 4 mg/kg and left for another 4 weeks without scarification.

Genetic polymorphism of 27 X-chromosomal short tandem repeats in an Egyptian population.

We presented allele frequencies of 27 X-chromosomal short tandem repeats (DXS6807, DXS9902, DXS6795, DXS6810, DXS10076, DXS10077, DXS10078, DXS10162, DXS10163, DXS10164, DXS7132, DXS981, DXS6800, DXS6803, DXS6809, DXS6789, DXS6799, DXS7424, DXS101, DXS7133, GATA172D05, DXS10103, HPRTB, GATA31E08, DXS8377, DXS10147, and DXS7423) obtained from 352 unrelated individuals in Egypt. No deviation from Hardy-Weinberg equilibrium was detected. Two pairs of adjacent loci showed significant linkage disequilibrium.

Sex determination by the length of metacarpals and phalanges: X-ray study on Egyptian population.

Measurements of hand bones length have been shown to be sexually dimorphic in many nationalities. The aim of this study is to assess the accuracy of sex determination from the length of all metacarpals and phalanges of right and left hands using X-ray radiographs and to develop a discriminant formula that can be used in the Egyptians. One hundred Egyptians are included in the study (50 adult males and 50 adult females) in the period from December 2009 to January 2011 with mean age 31.

Aflatoxin B1 level in relation to child's feeding and growth.

Objective: To study the influence of sociological factors, breast feeding and weaning on aflatoxin exposure in children as well as to determine the effect of aflatoxin exposure on child's growth.

Methods: A questionnaire, administered to the mothers of forty-six children, obtained information on the child's age, sex, residence, feeding, weaning and general health status. Maternal parity, education and occupation were also collected.

Prognostic significance of three hepatitis markers (p53 antibodies, vascular endothelial growth factors and alpha fetoprotein) in patients with hepatocellular carcinoma.

Background/aim: Hepatocellular carcinoma (HCC) is the third most common cause of cancer death in the world. Of patients with HCC, the diagnostic capacity of Alpha Fetoprotein (AFP) depends on its elevation in the serum. Concentration of AFP greater than the upper reference limit indicate the presence of HCC, but values below this level are less useful because they may also occur in chronic liver disease.