Publications by authors named "Doaa E Elhadedy"

The potential benefit of probiotics in small ruminant production systems has largely been unexplored. We evaluated the effect of a goat commercial probiotic on health and performance indicators in pastured goats from birth until 10 months. We randomly allocated 26 newborn nursing goat kids to two groups: a control group that received saline and a treatment group that received a commercial probiotic paste orally.

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Understanding gut lactic acid bacteria (LAB) in healthy hosts is an important first step in selecting potential probiotic species. To understand the dynamics of LAB in healthy goats, a cohort of thirty-seven healthy new-born goat kids was studied over a ten-month period. Total LAB was quantified using SYBR green qPCR.

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Streptomyces MDMMH4 cells were immobilized in various matrices with two different techniques for the enhanced and semi-continuous production of extracellular L-methioninase. Of these, agarose was proven to be the most suitable matrix for the immobilization of cells. The optimal agarose concentration was approximately 3% and the initial cell concentration was 150mg/ml (wet cell weight).

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Article Synopsis
  • The study explores the relationship between the microbiome and host transcriptomes in oral squamous cell carcinoma (OSCC) using advanced techniques beyond traditional 16S rRNA gene sequencing.
  • Analysis of tissue samples and healthy controls revealed a unique microbiome in OSCC that is low in abundance yet active, with specific bacteria and bacteriophages linked to cancer-related gene expression.
  • Findings suggest that interactions between the microbiome and host may contribute to oral cancer development, highlighting the need for further experimental validation of these mechanisms.
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