Publications by authors named "DoJin Kim"

This study focuses on fabricating a hybrid structure consisting of ZnO nanorods and ZnTe nanoparticles for NO gas detection, particularly exploring the impact of light irradiation at room temperature (RT). The morphology, physical characteristics, and chemical properties of the ZnO/ZnTe hybrid structure are carefully studied under diverse analytical methods such as X-ray diffraction (XRD), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and other measurements. The ZnO/ZnTe composite displayed an improved response toward 500 ppb NO under the blue light radiation effect.

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New photostable and bright supramolecular complexes based on cucurbit[7]uril (CB7) host and diketopyrrolopyrole (DPP) guest dyes having two positively charged 4-(trimethylammonio)phenyl groups were prepared and characterized. The dye core displays large Stokes shift (in HO, abs./emission max.

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Article Synopsis
  • Proper lipid metabolism is essential for the function of alveolar epithelial cells (AECs), and excessive AEC death contributes to idiopathic pulmonary fibrosis (IPF).
  • Research shows that the enzyme fatty acid synthase (FASN) is downregulated in the lungs of IPF patients, and its overexpression can protect AECs from death caused by bleomycin.
  • Enhancing FASN levels may improve mitochondrial function and reduce lung inflammation and fibrosis, presenting a potential therapeutic avenue for IPF treatments.
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Photoswitchable fluorophores─proteins and synthetic dyes─whose emission is reversibly switched on and off upon illumination, are powerful probes for bioimaging, protein tracking, and super-resolution microscopy. Compared to proteins, synthetic dyes are smaller and brighter, but their photostability and the number of achievable switching cycles in aqueous solutions are lower. Inspired by the robust photoswitching system of natural proteins, we designed a supramolecular system based on a fluorescent diarylethene () and cucurbit[7]uril (CB7) (denoted as @CB7).

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Afterglow is superior to other optical modalities for biomedical applications in that it can exclude the autofluorescence background. Nevertheless, afterglow has rarely been applied to the high-contrast "off-to-on" activatable sensing scheme because the complicated afterglow systems hamper the additional inclusion of sensory functions while preserving the afterglow luminescence. Herein, a simple formulation of a multifunctional components-incorporated afterglow nanosensor (MANS) is developed for the superoxide-responsive activatable afterglow imaging of cisplatin-induced kidney injury.

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Hematite-based photoanode (α-FeO) is considered the promising candidate for photoelectrochemical (PEC) water splitting due to its relatively small optical bandgap. However, severe charge recombination in the bulk and poor surface water oxidation kinetics have limited the PEC performance of FeO photoelectrodes, which is far below the theoretical value. Herein, a new catalyst, S-doped FeOOH (S-FeOOH), has been immobilized onto the surface of the FeO nanorod (NR) array by a facile chemical bath deposition incorporated thermal sulfuration process.

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Hybrid nanostructures are promising for ultrasound-triggered drug delivery and treatment, called sonotheranostics. Structures based on plasmonic nanoparticles for photothermal-induced microbubble inflation for ultrasound imaging exist. However, they have limited therapeutic applications because of short microbubble lifetimes and limited contrast.

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During the past few decades, photoelectrochemical (PEC) water splitting has attracted significant attention because of the reduced production cost of hydrogen obtained by utilizing solar energy. Significant efforts have been invested by the scientific community to produce stable ternary metal oxide semiconductors, which can enhance the stability and increase the overall production of oxygen. Herein, we present the ternary metal oxide deposition of ZnCoO as a route to obtain a novel photocatalyst layer on BiVO to form BiVO/ZnCoO a novel composite photoanode for PEC water splitting.

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Background: Epidermal growth factor receptor (EGFR) mutations in non-small-cell lung cancer predict sensitivity to EGFR tyrosine kinase inhibitors (TKIs). EGFR mutation types are associated with efficacy of EGFR TKIs. We investigated the clinical outcomes of afatinib, erlotinib, and gefitinib according to EGFR mutation type in patients with lung adenocarcinoma.

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Photoelectrochemical water splitting is an environmentally benign way to store solar energy. Properties such as fast charge recombination and poor charge transport rate severely restrict the use of BiVO as a photoanode for photoelectrochemical water splitting and many attempts were made to improve the current performance limit of the photoanode. To address these disadvantages, a highly efficient BiVO/BiS heterojunction was fabricated applying facial anion-exchange (AE) and successive ionic layer adsorption and reaction (SILAR).

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Background: Calprotectin is the major cytosolic protein in neutrophil granulocytes. Although asthma is known to cause eosinophilic inflammation, some patients with asthma have non-eosinophilic inflammation, which is characterized by local neutrophilic inflammation. The aim of this study was to assess calprotectin expression levels in a mouse model of asthma, and to observe the relationship of serum calprotectin level and clinical variables in patients with asthma.

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A hydrogen breath test is a non-invasive and safe diagnostic tool to explore the functional gastrointestinal disorders. For the diagnosis of small intestinal bacterial overgrowth syndrome as well as carbohydrate malabsorption such as fructose, lactose, and sorbitol malabsorption, a hydrogen breath test is considered one of the gold criterions. Since the more sensitive hydrogen sensor enables the more accurate prediction about the disease, many efforts have been to the development of the high performance H sensor.

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Inhaled capsaicin (8-methyl--vanillyl-6-nonenamide) has been used to induce cough in a safe and dose-dependent manner. Chronic cough is associated with an increased sensitivity to inhaled capsaicin in patients with asthma. The aim of this study was to evaluate clinical impact of capsaicin provocation test for chronic cough, and to find relationship between capsaicin concentration producing coughs and clinical variables in patients with asthma.

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Tin sulfide (SnS) is known for its effective gas-detecting ability at low temperatures. However, the development of a portable and flexible SnS sensor is hindered by its high resistance, low response, and long recovery time. Like other chalcogenides, the electronic and gas-sensing properties of SnS strongly depend on its surface defects.

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Recently, III-nitride semiconductor nanostructures, especially InGaN/GaN quantum well nanorods (NRs), have been established as a promising material of choice for nanoscale optoelectronics and photoelectrochemical (PEC) water-splitting applications. Due to the large number of surface states, III-nitride NRs suffer from low quantum efficiency. Therefore, control of the surface states is necessary to improve device performance in real-time applications.

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Adenocarcinoma is the most common type of non-small cell lung cancer. Some causative genomic alterations in epidermal growth factor receptor (EGFR), including deletions in exon 19 (E19 dels) and a point mutation in E21, are known to have favourable prognoses due to sensitivity to tyrosine kinase inhibitors; however, the prognoses of other uncommon mutations are unclear. This study analysed the clinical significance of EGFR mutation types in lung adenocarcinoma.

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Nanocomposite structures, where the Fe, FeO, or NiO nanoparticles with thin carbon layers are distributed among a single-wall carbon nanotube (SWCNT) network, are architectured using the co-arc discharge method. A synergistic effect between the nanoparticles and SWCNT is achieved with the composite structures, leading to the enhanced sensing response in ammonia detection. Thorough studies about the correlation between the electric properties and sensing performance confirm the independent operation of the receptor and transducer in the sensor structure by nanoparticles and SWCNT, respectively.

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Two-dimensional (2D) nanomaterials have distinct optical and electrical properties owing to their unique structures. In this study, smooth 2D amorphous tin disulfide (SnS) films were fabricated by atomic layer deposition (ALD), and applied for the first time to photoelectrochemical water splitting. The optimal stable photocurrent density of the 50-nm-thick amorphous SnS film fabricated at 140 °C was 51.

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Dual-emissive systems showing color-specific photoswitching are promising in bioimaging and super-resolution microscopy. However, their switching efficiency has been limited because a delicate manipulation of all the energy transfer crosstalks in the systems is unfeasible. Here, we report a perfect color-specific photoswitching, which is rationally designed by combining the complete off-to-on fluorescence switching capability of a fluorescent photochromic diarylethene and the frustrated energy transfer to the other fluorescent dye based on the excited-state intramolecular proton transfer (ESIPT) process.

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Organolead halide perovskite nanocrystals (NCs) have emerged as promising materials for various optoelectronic applications. However, their practical applications have been limited due to low structural integrity and poor luminescence stability associated with fast attachment-detachment dynamics of surface capping molecules during postprocessing. At present, a framework for understanding how the functional additives interact with surface moieties of organolead halide perovskites is not available.

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Background: This study was planned to investigate the research trends related to naturally derived anti-inflammatory and anti-obesity components. The main purpose of this study was to find out and develop natural health cosmetic ingredients which has high effects on lipid degradation, moisturizing and elasticity enhancement.

Objective: We all hope this research provided systematic and practical data that can suggest an opportunity to further develop new products.

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Pruritus (itching) is classically defined as an unpleasant cutaneous sensation that leads to scratching behavior. Although the scientific criteria of classification for pruritic diseases are not clear, it can be divided as acute or chronic by duration of symptoms. In this study, we investigated whether skin injury caused by chemical (contact hypersensitivity, CHS) or physical (skin-scratching stimulation, SSS) stimuli causes initial pruritus and analyzed gene expression profiles systemically to determine how changes in skin gene expression in the affected area are related to itching.

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A paramagnetic NiTi substrate was coated with diamagnetic carbon materials, i.e., graphene, graphene oxide (GO), and carbon nanotubes (CNTs), in order to reduce magnetic resonance (MR) image artifacts of NiTi implants.

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In gas sensors, metal oxide semiconductors have been considered as favorable resistive-type toxic gas sensing materials. However, the higher temperature operation of metal oxides becomes a barrier for their wide range of applications in explosive and flammable gas environments. In this regard, great efforts have been devoted to reducing the operating temperature of the sensor.

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Recently, printable nanomaterials have drawn tremendous attention for low-cost, large-area electronics applications. In particular, metallic nanoparticles that can facilitate the formation of highly functioning electrodes are indispensable constituent nanomaterials. In this paper, we propose printable mixed inks comprising multicomponent ingredients of Cu, Ni and Cu/CuSn core/shell nanoparticles.

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