Thermoresponsive fiber-based microwells capable of formation and retrieval of salivary gland stem cell spheroids for the regeneration of irradiation-damaged salivary glands.

Three-dimensional spheroid culture enhances cell-to-cell interactions among stem cells and promotes the expression of stem cell properties; however, subsequent retrieval and delivery of these cells remain a challenge. We fabricated a thermoresponsive fiber-based microwell scaffold by combining electrospinning and hydrogel micropatterning. The resultant scaffold appeared to facilitate the formation of cellular spheroids of uniform size and enabled the expression of more stem cell-secreting growth factor genes (, , , , and ), pluripotent stem cell-related genes ( and ), and adult epithelial stem cell-related genes (, , and ) than salivary gland stem cells in a monolayer culture (SGSC).

Road Speed Prediction Scheme by Analyzing Road Environment Data.

Road speed is an important indicator of traffic congestion. Therefore, the occurrence of traffic congestion can be reduced by predicting road speed because predicted road speed can be provided to users to distribute traffic. Traffic congestion prediction techniques can provide alternative routes to users in advance to help them avoid traffic jams.

3D Organoid Culture From Adult Salivary Gland Tissues as an Modeling of Salivary Gland Morphogenesis.

Lumen formation of salivary glands has been investigated using or rudiment culture models. In this study, we used a three-dimensional (3D) salivary gland organoid culture system and demonstrated that lumen formation could be recapitulated in mouse SMG organoids. In our organoid culture system, lumen formation was induced by vasoactive intestinal peptide and accelerated by treatment with RA.

User Recommendation for Data Sharing in Social Internet of Things.

As various types of data are generated on the social Internet of things (SIoT), which combine the Internet of things (IoT) and social networks, the relations of IoT devices should be established for necessary data exchange. In this paper, we propose a user recommendation scheme that facilitates data sharing through an analysis of an interaction between an IoT device and a user in the SIoT. An interrelation between a user and an IoT device as well as an interrelation between users exist simultaneously in the SIoT.

Detecting Incremental Frequent Subgraph Patterns in IoT Environments.

As graph stream data are continuously generated in Internet of Things (IoT) environments, many studies on the detection and analysis of changes in graphs have been conducted. In this paper, we propose a method that incrementally detects frequent subgraph patterns by using frequent subgraph pattern information generated in previous sliding window. To reduce the computation cost for subgraph patterns that occur consecutively in a graph stream, the proposed method determines whether subgraph patterns occur within a sliding window.