Publications by authors named "DoHyeon Yu"

The objective of this study was to describe the incidence, breed distribution, clinical findings (anatomic location, number of testicles affected, and side), and surgical management of cryptorchidism in dogs and cats presented for elective gonadectomy. Medical record abstracts from a non-profit, high-volume, high-quality, spay-neuter clinic from 2018 to 2023 were reviewed retrospectively for cases of elective surgical gonadectomy of cryptorchid dogs and cats. During the study period, 5,476 dogs and 11,559 cats were presented to the same facility for elective surgical castration, suggesting a cryptorchid incidence of 3.

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Hamartoma is characterized by the abnormal proliferation of cells and tissues within the originating organ. Apocrine hamartoma (AH) affecting the skin, especially in the perianal area, has not yet been reported in dogs. A 7-year-old neutered male Poodle presented with multiple perianal papules and pruritus.

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Li-CO batteries (LCBs) have emerged as promising solutions for energy storage, with the added benefit of contributing to carbon neutrality by capturing and utilizing CO during operation. In this study, a high-performance LCB was developed using a Ge-doped LiAlGeTi (PO) (LAGTP) solid electrolyte, which was synthesized via a solution-based method by doping Ge into NASICON-type LATP. The ionic conductivity of the LAGTP pellets was measured as 1.

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Background: Nucleated red blood cells (nRBCs) are increased by disease processes and hematopoietic stress.

Objectives: To evaluate the utility of nRBCs as a marker of disease severity and prognosis in dogs with systemic inflammatory response syndrome (SIRS).

Animals: Sixty-two client-owned dogs met the criteria of SIRS without anemia.

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Background: The effect of acidemia on blood coagulation remains inadequately understood in veterinary medicine. Therefore, we assessed the effect of acidification of canine whole blood on coagulation and investigated whether acidemia-induced coagulopathy could be reversed by reversing acidemia.

Methods: Citrated whole blood samples were taken from six healthy Beagle dogs and categorized, based on pH adjustment, into neutral, weak acidemia (WA), strong acidemia (SA), and reversal from SA.

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Background: Calf diarrhea leads to high mortality rates and decreases in growth and productivity, causing negative effects on the livestock industry. Lactate is closely associated with metabolic acidosis in diarrheic calves. However, there have been no reports on lactate concentrations in Korean indigenous (Hanwoo) calves, especially those with diarrhea.

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7409N31 was isolated from the feces of a healthy 11-day-old Hanwoo calf from a farm in Geochang-gun, Gyeongsangnam-do, Korea. The genome of the strain was completely sequenced using the PacBio RSII sequencing system, and it was confirmed that it was composed of one circular chromosome. The size of the entire genome was 2,198,442 bp, and it had 35.

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Introduction: Aberrant lymphoma phenotypes are frequently found in dogs, but the clinical implications are sparse.

Methods: Twenty-seven dogs with aberrant lymphoma diagnosed using flow cytometry between 2017 and 2023 were analyzed. Major paraneoplastic syndromes, prognostic factors, and clinical features of lymphoma were compared to their immunophenotypes.

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Siewert-Kartagener's syndrome, a type of primary ciliary dyskinesia, is a complex disease comprising situs inversus, rhinosinusitis, and bronchiectasis. Situs inversus totalis is a condition in which all organs in the thoracic and abdominal cavities are reversed. Furthermore, primary ciliary dyskinesia, an autosomal genetic disease, may coexist with situs inversus totalis.

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Background: The association of gut microbiota with cancer etiology and prognosis has been demonstrated in humans and rodents but has not been studied in dogs with different types of tumors.

Hypothesis/objectives: To analyze microbiome composition according to tumor progression based on metastasis, recurrence, and therapeutic response in canine tumors.

Animals: Thirty-two client-owned dogs were divided into 3 groups: healthy (n = 9), with lymphoma (n = 12), with nonlymphoid tumors (n = 11).

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Lymphoma is a severe condition characterized by the proliferation of neoplastic lymphoid cells. A 4-year-old female mongrel dog presented with solitary lymph node enlargement. Significant right prescapular lymphadenopathy and abdominal enlargement were observed during physical examination.

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Despite various treatment options for canine atopic dermatitis (cAD), therapeutic limitations still exist, including adverse effects and low absorption ratios. This study evaluated the effects of a membrane-free stem cell extract (MFSCE) on the clinical signs of atopic dogs. Thirty client-owned dogs previously diagnosed with cAD were separated into placebo ( = 10) and MFSCE-treated groups ( = 20).

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Feline hemotropic mycoplasmosis (hemoplasmosis) is an infection of the red blood cells caused by the Mycoplasma haemofelis (Mhf), Candidatus Mycoplasma haemominutum (CMhm), and Candidatus Mycoplasma turicensis (CMt). The existence of Mhf, CMhm, and CMt has been demonstrated in feral cats in Korea using molecular methods, but no clinical cases have yet been reported. This study reports 2 clinical cases of hemotropic mycoplasmosis caused by CMhm and CMt in 2 anemic cats.

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We report a rare case of sterile neutrophilic dermatosis (Sweet's syndrome) accompanied by systemic inflammatory response syndrome. A 5-year-old, neutered male Maltese dog presented with extensive crusts on the whole-body surface and multifocal erosions and plaques on the four limbs. The lesions had been present for two months and did not respond to antibiotics before the presentation.

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Leukaemia cutis (LC) is the infiltration of neoplastic leukocytes into the skin, characterised by haemorrhagic papules, nodules, and plaques. LC has been reported in human leukaemia patients, but it is extremely rare in dogs. A 13-year-old spayed female Golden Retriever that was previously diagnosed with chronic lymphocytic leukaemia was managed with chlorambucil (20 mg/m orally, every 2 weeks) and prednisolone (2 mg/kg orally, every other day) for 8 months; however, immunosuppression was temporarily discontinued because of a bacterial urinary tract infection.

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Bacillus amyloliquefaciens is a gram-positive bacterial species that is utilised as a probiotic in humans and animals. There are no reports of infective endocarditis (IE) in dogs. An 8-year-old, spayed, female Maltese presented with a 1-month history of fever, depression, weight loss, and hindlimb lameness.

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Article Synopsis
  • Strain 1394N20 is a bacterium isolated from the feces of healthy Hanwoo calves, indicating its presence in the intestinal flora of livestock.
  • Its genome consists of a single circular chromosome with over 2.2 million base pairs, containing genes for 2,281 proteins, 15 rRNAs, and 65 tRNAs.
  • The strain encodes an enzyme called endoglucanase, which breaks down complex carbohydrates, suggesting its potential use as a probiotic to improve nutrient digestibility in animals.
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Cell-free DNA (cfDNA) is derived from apoptosis/necrosis, active cellular secretion, and lysis of circulating cancer cells or micrometastases. In humans, cfDNA is widely used in cancer diagnosis, but veterinary research has yet to be actively conducted to establish it as a cancer biomarker. This retrospective study analyzed cfDNA levels in samples collected from dogs with neoplastic disease ( = 38), clinically ill dogs without neoplasia ( = 47), and healthy dogs ( = 35).

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This study aimed to identify potential biomarkers of canine pyometra and their correlations with clinical parameters. First, 90 dogs with pyometra and 26 healthy female dogs were compared. Then, paired samples (before and after ovariohysterectomy) from 22 dogs with pyometra and 9 healthy controls from the initial cohort were compared.

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Infectious calf diarrhea is one of the most significant diseases of neonatal calves. This study is conducted to identify the prevalence of pathogens in calf diarrhea for 2 years. A total of 544 feces samples from Korean native beef calves were obtained to investigate selected seven pathogens causing calf diarrhea: bovine rotavirus, bovine coronavirus, , bovine viral diarrhea virus, species, K99, and species.

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Article Synopsis
  • Interleukin-15 (IL-15) is a special protein that helps the immune system fight infections and can also be used to treat cancer.
  • In this study, healthy dogs received a new form of IL-15 for 8 days to see if it was safe and how it affected their immune system.
  • The treatment was safe with no serious side effects, and it helped activate important immune cells that can fight cancer in dogs.
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Bovine coronavirus (BCoV) is associated with severe diarrhea, dehydration, and depression, which result in significant economic damages in the dairy and beef cattle industries worldwide. However, differences in the gut microbiota structure and their correlations with differing physiological parameters between BCoV-infected calves with diarrhea and recovered calves are not well understood. In this study, fecal specimens were collected from 10 post-weaned calves, before and after 2 months of fluid therapy, and the samples were used for microbiota analysis.

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Serum proteins are involved in the regulation of inflammation, and therefore, serum protein profiling provides important insights in diverse inflammatory reactions. Accordingly, concentrations of single APPs, such as the C-reactive protein (CRP), serum amyloid A (SAA), and haptoglobin (Hp), have been described as indicators of inflammatory response in canine pyometra. However, there is little information regarding the overall serum protein profile obtained by SPE in canine pyometra.

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Calf diarrhea leads to substantial economic losses in the livestock industry worldwide due to medical treatment costs, retarded growth performance, and even death. The objective of this study was to investigate changes in serum protein profiles and acute phase proteins in calves with diarrhea and identify the association between these changes and diarrhea. A total of 185 Korean beef calves were used and divided into 3 groups by age: 1 to 10 days ( = 46), 11 to 20 days ( = 65), and 21 to 30 days ( = 74).

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A 1-year-old, castrated, male, domestic short-haired cat with pruritic, multifocal, crusted ulceration of the skin over the dorsal aspect of the neck and scapulae was presented. The cat also had a history of depression and anorexia. A causative agent for the lesion was not identified on a general dermatological examination.

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