Validation of Active Compound of L. Extract and Its Anti-Inflammatory and Antioxidant Properties by Regulating Mitochondrial Dysfunction and Cellular Signaling Pathways.

As chronic inflammation and oxidative stress cause various diseases in the human body, this study aimed to develop functional materials to prevent inflammation and oxidative stress. This study investigated the biological function and components of L. extract prepared using its leaves and branches (TCE).

Amenyunnaosides A-C, Three New Neolignans Isolated from Amentotaxus yunnanensis and Their Anti-inflammatory Activities.

Phytochemical study on the leaves of Amentotaxus yunnanensis led to the isolation of seventeen phenolic compounds including sixteen neolignans and lignans, and one flavone glycoside. Three among the isolates were previously unreported neolignans and named as amenyunnaosides A-C, respectively. Their structures were elucidated by extensive analyses of HR-ESI-MS, 1D and 2D NMR, and ECD spectra.

(Capparaceae), a new species from central Vietnam.

Sy & D.V. Hai, a new species from Kbang District, Gia Lai Province, Vietnam, is described and illustrated.

(Apocynaceae, Asclepiadoideae), a new species from Vietnam.

(Apocynaceae, Asclepiadoideae), a new species from Vietnam is described, illustrated and compared with the similar species Kerr. differs from by the morphology of the rachis of the inflorescence, the margins of the corolla lobes and the colour of the adaxial surface of the corolla.

Ethnobotanical study on medicinal plants used by local Van Kieu ethnic people of Bac Huong Hoa nature reserve, Vietnam.

Ethnopharmacological Relevance: The ethnobotanical survey was carried out in the Bac Huong Hoa Nature Reserve (BHHNR), Vietnam. The Van Kieu ethnic group, the inhabitant of Nature Reserve, is rich in knowledge about the medicinal plants found in the Nature Reserve. However, their knowledge is less documented.

Premna vietnamensis (Lamiaceae, Premnoideae), a distinct new species from the Central Highlands of Vietnam.

Premna vietnamensis, a distinct new species which is endemic to Gia Lai Province in Central Highlands of Vietnam, is described and illustrated. It is characterized by its calyx tube bearing a semi-globose fleshy appendage, which has not been reported before from all known congeneric taxa, as well as from the Lamiaceae. A phylogenetic analysis of the whole Lamiaceae based on a sampling including representatives from all 12 currently recognized subfamilies confirmed the placement of this new species within Premna of the Premnoideae.

Enrichment of genomic resources and identification of simple sequence repeats from medicinally important .

To broaden and delve into the genomic information of , an important medicinal plant in many Asian countries, RNA sequencing (RNA-seq) analysis was performed and a total of 16,638 non-redundant unigenes (≥ 300 bp) with an average length of 755 bp were generated by de novo assembly from 17,580,456 trimmed clear reads. The functional categorization of the identified unigenes by a gene ontology (GO) term resulted in 2305 genes in the cellular component, 5577 in the biological processes, and 8056 in the molecular functions, respectively. The top sub-category in biological processes was the metabolic process with 4374 genes.

Inhibition of the Calcineurin Pathway by Two Flavonoids Isolated from Finet & Gagnep.

In order to discover plant-derived signaling pathway inhibitors with antifungal properties, a two-component screening system utilizing the calcineurin and Hog1 mitogen-activated protein kinase pathways responsible for the virulence networks of was employed, owing to the counter-regulatory actions of these pathways. Of the 1,000 plant extracts tested, two bioactive compounds from were found to act specifically on the calcineurin pathway of . These compounds, identified as pashanone and 5-hydroxy-6,7-dimethoxyflavanone, exhibited potent antifungal activities against various human pathogenic fungi with minimum inhibitory concentration values ranging from 4.

(Apocynaceae, Asclepiadoideae), a new species from Vietnam.

(Apocynaceae, Asclepiadoideae), a new species from Vietnam is described, illustrated and compared with its five congeners. differs distinctly from congeners by the longer peduncles (14-18 cm vs. 4 cm at most in and , salmon-pink color of the inner corolla lobes (white or greenish in the other species), and corolla tube length (12.

Clausena anisata-mediated protection against lipopolysaccharide-induced acute lung injury in mice.

Clausena anisata (Willd.) Hook.f.

Anti-inflammatory effects of methanol extract of Canarium lyi C.D. Dai & Yakovlev in RAW 264.7 macrophages and a murine model of lipopolysaccharide-induced lung injury.

Canarium lyi C.D. Dai & Yakovlev (CL) is a member of the Anacardiaceae family.

Anti-inflammatory activities of methanol extract of Mastixia arborea C.B. Clarke as to mouse macrophage and paw edema.

The biological activity of Mastixia arborea (MA) relates to inflammation, but the underlying mechanisms are largely unknown. We confirmed the anti-inflammatory effects of a methanol extract of MA extract on lipopolysaccharide (LPS)-stimulated RAW264.7 mouse macrophage cells and carrageenan-induced mice paw edema.