Publications by authors named "Do Duc Que"
Article Synopsis
- Two new fungal pigments, schweinitzins A and B, along with two other compounds, were extracted from the fruit bodies of Xylaria schweinitzii found in Vietnam.
- Their structures were determined using various spectroscopic techniques including IR, UV-Vis, and NMR.
- Compounds schweinitzins A and (S)-torosachrysone-8-O-methyl ether exhibited significant cytotoxic effects against multiple cancer cell lines, indicating potential therapeutic value.
Phytochemical study on the methanol extract of the fruit bodies of Vietnamese fungus Daldinia concentrica has led to the isolation and structural elucidation of three cytotoxic constituents, 6,8-dihydroxy-3-methyl-3,4-dihydroisocoumarin (1), (22R)-hydroxylanosta-7,9(11),24-trien-3-one (2) and ergosterol (3). Their structures were elucidated by 2D-NMR and FT-ICR-MS. All the three compounds showed moderate cytotoxicity against four cancer cells, KB (a human epidermal carcinoma), MCF7 (human breast carcinoma), SK-LU-1 (human lung carcinoma) and HepG2 (hepatocellular carcinoma).
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