Publications by authors named "Dmytro Palets"
Dynamics of nucleosomes and their interactions are important for understanding the mechanism of chromatin assembly. Internucleosomal interaction is required for the formation of higher-order chromatin structures. Although H1 histone is critically involved in the process of chromatin assembly, direct internucleosomal interactions contribute to this process as well.
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- The Holliday junction (HJ) is crucial for DNA processes like recombination, and its branch migration can occur spontaneously or with protein help, requiring the HJ to unfold.
- Previous studies suggest that branch migration is stepwise, but folding can halt this process.
- This research aimed to investigate how DNA nicks affect HJ dynamics and migration efficiency, revealing that while nicks don't stop migration, they significantly alter the structure and behavior of the HJ.