Publications by authors named "Dmitry Vetushko"
Article Synopsis
- * A study estimated treatment success probabilities for different BDQ durations (6 months, 7-11 months, and 12 months or more) among patients on individualized longer regimens, using methods to mitigate biases.
- * Results showed that treatment success rates were similar for BDQ durations of 6 months (85%) and 12 months (86%), while the 7-11 month group had a lower success rate (77%); extending BDQ beyond 6 months did not improve outcomes, highlighting the need for careful analysis in
Background: Concomitant use of bedaquiline (Bdq) and delamanid (Dlm) for multi-drug/rifampicin resistant tuberculosis (MDR/RR-TB) has raised concerns about a potentially poor risk-benefit ratio. Yet this combination is an important alternative for patients infected with strains of TB with complex drug resistance profiles or who cannot tolerate other therapies. We assessed safety and treatment outcomes of MDR/RR-TB patients receiving concomitant Bdq and Dlm, along with other second-line anti-TB drugs.
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