Publications by authors named "Dmitry Puchinsky"
Horm Metab Res
December 2019
Article Synopsis
- The global rise in diabetes cases is linked to β-cell dysfunction, which affects insulin production in both type 1 and type 2 diabetes.
- Traditional drug evaluations in the pharmaceutical industry rely on cell lines and rodent models, which do not accurately replicate human islet function, limiting the predictive power for new diabetes treatments.
- The innovative Engineered Micro-Pancreas, utilizing a decellularized lung-derived scaffold and human islets, shows promising viability and insulin secretion comparable to human islets, paving the way for more effective drug discovery methods.
