Crystal structures of 4-(2/3-meth-oxy-phen-oxy)phthalo-nitrile.

The syntheses and crystal structures are reported of 4-phen-oxy-substituted phthalo-nitriles with meth-oxy groups in the - and -positions of the terminal benzene rings, respectively, namely, 4-(2-meth-oxy-phen-oxy)phthalo-nitrile and 4-(3-meth-oxy-phen-oxy)phthalo-nitrile, both CHNO. The https://journals.iucr.

Synthesis, Spectroscopic Properties and Redox Behavior Kinetics of Rare-Earth Bistetrakis-4-[3-(3,4-dicyanophenoxy)phenoxy]phthalocyaninato Metal Complexes with Er, Lu and Yb.

Novel bistetrakis-4-[3-(3,4-dicyanophenoxy)phenoxy]phthalocyaninato of complexes erbium, lutetium and ytterbium were synthesized using a template fusion method to prevent any polymerization process. The complexes were separated from the reaction mixtures and characterized by NMR, IR and electron absorption spectroscopy. The spectroscopic properties of the metal phthalocyaninates in chloroform, acetone and tetrahydrofuran were studied.

A Route to Triazole-Fused Sultams via Metal-Free Base-Mediated Cyclization of Sulfonamide-Tethered 5-Iodotriazoles.

An efficient direct approach to triazole-fused sultams has been developed. The key step of the proposed strategy is base-mediated cyclization of sulfonamide-tethered 5-iodo-1,2,3-triazoles which are readily available via an improved protocol for Cu-catalyzed 1,3-dipolar cycloaddition. The annulation of the sultam fragment to the triazole ring proceeds smoothly under transition-metal-free conditions in the presence of CsCO in dioxane at 100 °C and affords fused heterocycles in high yields up to 99%.

A novel approach to a controlled opening of liposomes.

A novel strategy is described for preparing pH-sensitive liposomes which releases the encapsulated drug in response to the change in pH of surrounding solution. The liposomes, composed of conventional zwitter-ionic egg yolk lecithin (EL), additionally contains a pH-sensitive "activator" (AMS), a derivative of lithocholic acid with anionic and cationic groups attached to the opposite ends of the steroid core. AMS changes its orientation in the liposomal membrane thus adapting to acidity/basicity of the outer solution.

Annulation-Induced Cascade Transformation of 5-Iodo-1,2,3-triazoles to 2-(1-Aminoalkyl)benzoxazoles.

Base-mediated cyclization of (5-iodo-1,2,3-triazolyl)phenols was proposed as a new synthetic strategy for the in situ generation of diazoimines via electrocyclic ring opening of the fused heterocycle. Cu-catalyzed amination of the intermediate diazoalkanes was employed to develop an efficient cascade approach to functionalized benzoxazoles.