Larval stress affects adult Drosophila behavior and metabolism.

In this study, we raised the following question: "Does metamorphosis, being a "reboot" of all systems of the organism, erase the changes that occurred at earlier stages of insect development?" To answer this question, we investigated several behavioral, metabolic and neuroendocrine parameters in Drosophila melanogaster imago that had undergone heat stress at the 3rd larval instar (32 °C, 48 h). We discovered that larval stress negatively affected feeding and locomotor behavior, as well as total lipid content in adult flies. At the same time, these flies demonstrated a considerable increase in carbohydrate content and expression level of insulin/insulin-like growth factor signaling (IIS) pathway genes, dfoxo, dilp6 and dInR.

Association between the Effects of High Temperature on Fertility and Sleep in Female Intra-Specific Hybrids of .

Humans and fruit flies demonstrate similarity in sleep-wake behavior, e.g., in the pattern of sleep disturbances caused by an exposure to high temperature.