Being a close analogue of amflutizole, methyl 4-amino-3-phenylisothiazole-5-carboxylate (CHNOS) was assumed to be capable of forming polymorphic structures. Noncentrosymmetric and centrosymmetric polymorphs have been obtained by crystallization from a series of more volatile solvents and from denser tetrachloromethane, respectively. Identical conformations of the molecule are found in both structures.
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