Introduction: Low sexual desire is a frequent sexual problem in women, with only one drug for the condition approved by the Food and Drug Administration.
Aim: To evaluate the ability of a novel synthetic peptide, BP101, to facilitate sexual behavior after intranasal administration or infusion into certain brain areas in female rats.
Methods: Bilaterally ovariectomized female rats, primed with a suboptimal combination of estradiol benzoate (EB) and progesterone, were used as a model of low sexual motivation.