Repurposing Antihypertensive and Statin Medications for Spinal Pain: A Mendelian Randomization Study.

Study Design: Mendelian randomization (MR) study.

Objective: To examine whether antihypertensive medications (beta-blockers, calcium channel blockers, and angiotensin-converting enzyme inhibitors) and statins can be repurposed to prevent or treat spinal pain (back or neck pain).

Summary Of Background Data: Observational studies and a recent MR study have found associations between elevated blood pressure and a greater risk of back pain.