Publications by authors named "Dmitrii A Reshetnikov"
Immunogenicity and Protectivity of Sputnik V Vaccine in hACE2-Transgenic Mice against Homologous and Heterologous SARS-CoV-2 Lineages Including Far-Distanced Omicron BA.5.
Inna V Dolzhikova Amir I Tukhvatulin Daria M Grousova Ilya D Zorkov Marina E Komyakova Dmitrii A Reshetnikov
Vaccines (Basel)
October 2024
Article Synopsis
- The SARS-CoV-2 virus mutates continuously, leading to new variants like Omicron, which has reduced the effectiveness of vaccines worldwide.
- The study evaluated the Sputnik V vaccine's effectiveness against several SARS-CoV-2 variants using various research methods on transgenic mice.
- Results showed that while Sputnik V generates a strong immune response, its efficacy is significantly lower against the Omicron variant, highlighting the need for ongoing monitoring and potential development of new vaccines.