Publications by authors named "Dmitri E Kamashev"
We present a systematic study of three bacterial species that belong to the class Mollicutes, the smallest and simplest bacteria, Spiroplasma melliferum, Mycoplasma gallisepticum, and Acholeplasma laidlawii. To understand the difference in the basic principles of metabolism regulation and adaptation to environmental conditions in the three species, we analyzed the metabolome of these bacteria. Metabolic pathways were reconstructed using the proteogenomic annotation data provided by our lab.
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- Tuberculosis caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains is increasingly problematic in various countries, prompting a study on the genetic differences among them.
- Researchers sequenced genomes from Russian MTB strains, including drug-susceptible, MDR, and XDR strains, and found they belong to different genetic families, complicating direct comparisons.
- A comprehensive analysis revealed unique non-synonymous SNPs associated with drug resistance and functional categories, highlighting mutational patterns that may aid XDR strains in evading antituberculosis treatments.