Publications by authors named "Djohra Hadef"
Objectives: To develop an easy-to-use and efficient clinical score to identify monogenic lupus based on clinical presentations and to stratify patients who may benefit from confirmatory molecular genetic testing.
Methods: A comprehensive literature review identified 55 distinct items across 12 clinical and laboratory domains, narrowed down to the top ten by a panel of 12 expert paediatric rheumatologists with 80% consensus. The proposed score was tested in a pilot study on 10 patients with monogenic lupus and 30 control subjects with various autoimmune and autoinflammatory diseases.
The inequity of global healthcare in pediatric rheumatology.
Best Pract Res Clin Rheumatol
September 2024
In pediatric rheumatology, global health inequity relates to the uneven distribution of healthcare resources, accessibility, and health outcomes among children with rheumatic conditions across various countries, regions, and socioeconomic groups. This inequity can manifest in various ways. This review article provides an overview of common rheumatic diseases, such as juvenile idiopathic arthritis and systemic lupus erythematosus, which significantly contribute to and are affected by disparities in global healthcare.
View Article and Find Full Text PDFEpidemiology and demographics of juvenile idiopathic arthritis in Africa and Middle East.
Pediatr Rheumatol Online J
December 2021
Article Synopsis
- Juvenile Idiopathic Arthritis (JIA) affects about 3 million children worldwide, with higher prevalence in girls and diverse influences from ethnicity and socioeconomic factors in Africa and the Middle East.
- Limited studies on JIA epidemiology in these regions highlight a lack of recent data, revealing a lower prevalence of JIA compared to global estimates, with oligoarticular arthritis as the most common subtype.
- Significant challenges in managing JIA exist, including the need for better data, increased disease awareness, local treatment guidelines, and more pediatric rheumatologists to address the unmet medical needs of affected patients.
Background: Pediatric Rheumatology is an orphan specialty in Africa which is gradually gaining importance across the continent.
Main Body: This commentary discusses the current state of affairs in the sphere of Pediatric Rheumatology across Africa and offers practical strategies to navigate the challenges encountered in research, models of care, education and training. We outline the establishment, opportunities of growth and achievements of the Pediatric Society of the African League Against Rheumatism (PAFLAR).
Article Synopsis
- The study aims to assess how rheumatology services in Africa have changed due to the COVID-19 pandemic, using an online survey of rheumatologists across the continent.
- A total of 554 responses were collected from 20 African countries, revealing that many rheumatologists shifted toward virtual consultations while some still held face-to-face appointments with protective measures.
- The findings highlight significant regional differences in the adaptation to the pandemic, including the creation of national guidelines and the availability of COVID-19 registries for rheumatology.