Therapeutic Efficacy of Extract and Silver Nanoparticles Synthesized from the Extract against Cadmium-Induced Renal Nephrotoxicity in Wistar Rats.

This study explored the therapeutic efficacy of and silver nanoparticles (Ag NPs) synthesized using a extract to alleviate cadmium-induced nephrotoxicity in Wistar rats. Sub-acute toxicity assessments of (100 mg/kg, 1000 mg/kg, and 4000 mg/kg) and Ag NPs (2 mg/kg and 10 mg/kg) did not find any significant difference, compared with untreated control rats ( = 3 animals/group). Then, the adult Wistar rats were divided into one control (untreated/unexposed) and six experimental groups ( = 5/group): Ag NPs alone, alone, exposure to 50 mg/kg CdCl in drinking water for 35 days, exposure to CdCl for 35 days followed by treatment with 0.

Therapeutic potential of silver nanoparticles from extract for mitigating cadmium-induced hepatotoxicity: liver function parameters, oxidative stress, and histopathology in wistar rats.

This study explores the therapeutic potential of silver nanoparticles (Ag NPs) synthesized using a extract in mitigating cadmium-induced hepatotoxicity in Wistar rats. Given the increasing environmental and health concerns associated with cadmium exposure, novel and eco-friendly therapeutic strategies are essential. Ag NPs were characterized using X-ray diffraction, UV-Vis spectrometry, and energy-dispersive X-ray spectroscopy with scanning electron microscopy, confirming their formation with a cubic crystal structure and particle sizes ranging from 4.