Early Detection of Renal Injury in Children with Sickle Cell Anaemia using Microalbuminuria in a Tertiary Health Institution in Southern Nigeria.

Background: Sickle cell anaemia (SCA), one of the causes of morbidity and mortality in children is associated with a large spectrum of systemic complications including sickle cell nephropathy (SCN). Microalbuminuria has been used as a marker of preclinical glomerular damage in these patients. This study aimed at detecting early, renal injury in children with SCA aged 1-17 years, highlighting associations and predictors of microalbuminuria in these children.

Liver aminotransferases in under-five HIV-positive children on HAART.

Background: Higher mortality rates were reported in developing countries during early months of HAART initiation than in developed countries. The study aimed at assessing the effect of Highly Active Antiretroviral Therapy (HAART) on liver function of under-fives.

Method: Two hundred and thirty-eight under-fives children were enrolled from five hospitals in Southern Nigeria.