Comparative evaluation of periodontally accelerated osteogenic orthodontics (PAOO) versus traditional camouflage orthodontic treatment in adult patients with skeletal class III malocclusion.

Background: Existing literature supports the efficacy of PAOO in augmenting alveolar bone volume and facilitating orthodontic tooth movement. However, there is a paucity of literature addressing its application in the treatment of adults with skeletal Class III malocclusion. This retrospective clinical study aimed to compare the clinical efficacy of camouflage orthodontic treatment combined with and without PAOO in adult patients presenting with skeletal Class III malocclusion.

Clinical Observations of Soft Tissue Dimensions Around Teeth and Implants After Free Gingival Graft.

Introduction And Aims: The histological and morphological differences in soft tissue between natural teeth and peri-implant may result in different clinical effectiveness to free gingival graft (FGG). This research aims to investigate the different efficacy of FGG in augmenting keratinized tissue width (KTW) between tooth and implant sites while evaluating its medium-term stability over a 2- to 5-year follow-up.

Methods: In this study, 29 patients underwent FGG to address insufficient clinical scenarios when KTW <2 mm at the buccal aspect, including 37 implant sites and 33 natural teeth sites both in posterior regions were included.

Comparison of immediate vs. delayed guided tissue regeneration in Infrabony defect of second molars after adjacent third molar extraction: a retrospective study.

Background: The distal aspect of the second molar (d-M2) often exhibits infrabony defects due to the adjacent third molar. Although the defects can be treated by guided tissue regeneration (GTR) after removing the third molar, the optimal timing remains uncertain following third molar removal in clinical decision-making. This study aimed to compare delayed and immediate GTR treatments to assist in clinical decision-making.

Yb-doped SnO electron transfer layer assisting the fabrication of high-efficiency and stable perovskite solar cells in air.

To date, most preparation processes of polycrystalline perovskite films still have to be performed in a glovebox filled with inert gas, limiting the application due to their high cost and complexity. In this work, we exploit a facile processing technique for the preparation of perovskite solar cells (PSCs) under ambient conditions by the Yb doping effect for SnO electron transfer layer. This remarkable and facile interface doping strategy promotes all-air processed planar PSCs, giving enhanced power conversion efficiency (PCE) from 15.

IL-35 may maintain homeostasis of the immune microenvironment in periodontitis.

T lymphocyte cells, including regulatory T (Treg) and T helper 17 cells, have important roles in the human periodontium. However, the basis for Treg cytokine expression in various compartments of the periodontium remains unclear. The aim of the present study was to investigate the expression of interleukin (IL)-35 in the peripheral blood mononuclear cells (PBMCs) and periodontal tissues of patients with chronic periodontitis (CP), with a view to understanding its role in this disease, and ultimately providing improved treatments.

[Expression and correlation of IL-35 in gingival crevicular fluid and serum with chronic periodontitis].

Purpose: To investigate the concentration of IL-35 in serum and gingival crevicular fluid (GCF) and the correlation between IL-35 and periodontal clinical parameters, and explore the possible role of IL-35 in chronic periodontitis (CP).

Methods: Twenty patients with moderate or severe chronic periodontitis were selected as experimental group and 20 healthy people were included as control group. The patients' baseline information, probing depth (PD) and clinical attachment level (CAL) were recorded.

[Effect of tamibarotene on innate immune response in the model of Porphyromonas gingivalis induced periodontitis].

Objective: To investigate the effect of Am80 on innate immune response of Porphyromonas gingivalis (Pg) W83-induced periodontitis in mice.

Methods: Twenty-five mice were randomly divided into five groups, control group, PgW83-induced periodontitis group (periodontitis), Am80 (10 µg/d) treatment group (low-dose group), Am80 (50 µg/d) treatment group (middle-dose group), Am80 (100 µg/d) treatment group (high-dose group). The distance of alveolar bone resorption in each mouse was observed and measured by a dissecting microscope.

[Characteristics of the immune status in aged mice with experimental periodontitis].

Purpose: To establish mice model with periodontitis by oral infection with Porphyromonas gingivalis, simulating human periodontal disease. The immune status of youth and aged mice were compared, and the cytokines expression of regulatory T cells and Th17 cells in this model were analyzed.

Methods: Entity microscope was used to evaluate the extent of periodontal bone resorption.

Tamibarotene modulates the local immune response in experimental periodontitis.

Tamibarotene (Am80), a synthetic retinoic acid receptor (RAR), is an agonist with high specificity for RARα and RARβ. Retinoid agonists have been shown to inhibit Th17 cell polarization and to enhance forkhead box P3 (Foxp3) expression during the course of inflammatory diseases. The aim of this study was to evaluate the previously unrecognized role of Am80 in regulating the immune responses of periodontitis within the oral microenvironment.

[Comparison of the IL-27 level in gingival crevicular fluid of cross-quadrant and the upper and lower half-mouth subgingival scaling].

Purpose: To investigate the changes of IL-27 in gingival crevicular fluid (GCF) before and after treatment with different methods for chronic periodontitis.

Methods: Sixty patients with moderate or severe chronic periodontitis were selected as study group to divide into group A (cross-quadrant) and group B (upper and lower half-mouth) randomly. Another 30 healthy people were selected as group C.