Publications by authors named "Dixi Huang"

Article Synopsis
  • * Xanthohumol (Xn), a compound known for its antioxidative and anti-inflammatory properties, was studied for its effects on obesity-related OA but lacked clear evidence prior to this research.
  • * The study concluded that Xn effectively reduces inflammation and cartilage degradation caused by palmitate by activating the AMPK signaling pathway, which improves mitochondrial function and inhibits harmful inflammatory responses.
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Extracellular vehicles play crucial function in osteosarcoma tumorigenesis.Extracellular vehicles mediated the intercellular communication of osteosarcoma cells with other types cells in tumor microenvironment.Extracellular vehicles have potential utility in osteosarcoma diagnosis and treatment.

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Article Synopsis
  • Osteoarthritis (OA) is a common degenerative joint disease where inflammation is crucial for its development; CAPE, a natural flavonoid, shows promise in reducing this inflammation.
  • In studies with IL-1β-stimulated chondrocytes and rat models, CAPE decreased harmful enzymes and inflammatory markers, while promoting substances that help maintain cartilage structure.
  • The findings suggest that CAPE could be a potential treatment or preventative measure for OA, as it effectively protects cartilage and slows disease progression.
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Background: Pre-hospitalisation, hospitalisation and post-hospitalisation factors may significantly affect depression, anxiety and post-traumatic growth (PTG) among COVID-19 survivors.

Objective: Our study investigated depression, anxiety and PTG and their correlates among COVID-19 survivors.

Method: A cross-sectional telephone survey recruited 199 COVID-19 patients (Mean age = 42.

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Background: As a highly infectious disease with human-to-human transmission characteristics, COVID-19 has caused panic in the general public. Those who have recovered from COVID-19 may experience discrimination and internalized stigma. They may be more likely to worry about social interaction and develop social anxiety.

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COVID-19 survivors who had acute respiratory symptoms might experience prolonged post-traumatic stress disorder (PTSD) due to further rehabilitation, somatic symptoms and related distress. The conservation of resource (COR) theory is a well-developed theory to understand how people develop PTSD symptoms in traumatic events. The current study aimed to examine the potential factors of PTSD symptoms and interrelationships among this factors among COVID-19 survivors based on the COR theory.

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Background: Many COVID-19 survivors reported stigmatization after recovery. This study investigated the association between stigma (discrimination experiences, self-stigma and perceived affiliate stigma) and sleep quality among COVID-19 survivors six months after hospital discharge.

Methods: Participants were recovered adult COVID-19 survivors discharged between February 1 and April 30, 2020.

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Background: Understanding factors associated with post-discharge sleep quality among COVID-19 survivors is important for intervention development.

Aims: This study investigated sleep quality and its correlates among COVID-19 patients 6 months after their most recent hospital discharge.

Method: Healthcare providers at hospitals located in five different Chinese cities contacted adult COVID-19 patients discharged between 1 February and 30 March 2020.

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Myostatin, a member of the transforming growth factor-β (TGF-β) superfamily, is a key autocrine/paracrine inhibitor of skeletal muscle growth. Recently, researchers have postulated that myostatin is a negative regulator of bone formation and metabolism. Reportedly, myostatin is highly expressed in the fracture area, affecting the endochondral ossification process during the early stages of fracture healing.

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