Publications by authors named "Divyah Nagendra"

Objective: To determine whether trust in the provider and sociodemographics are associated with individual-level abortion stigma.

Methods: We performed a cross sectional and exploratory study design using secondary analysis of a randomized trial that enrolled participants undergoing second trimester abortion. We collected baseline survey data from 70 trial participants to assess stigma (Individual Level of Abortion Stigma scale, ILAS; range 0-4), trust in provider (Trust in Physician scale; range 1-5), anxiety, depression, and sociodemographics.

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Article Synopsis
  • Early pregnancy loss, or miscarriage, is a prevalent issue in the U.S., affecting around 1 million people each year, and can be managed through different methods like medications or surgeries that vary in patient experience, effectiveness, and cost.
  • This study compared the cost-effectiveness of medical management with mifepristone and misoprostol to office uterine aspiration, analyzing data over a 30-day period and assessing factors like quality-adjusted life-years gained and costs.
  • Findings indicated that while office uterine aspiration had higher efficacy in complete gestational sac expulsion (97.3% vs 83.8%), medical management was more cost-effective and resulted in higher estimated quality-adjusted life-years gained.
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Objective: To compare the overnight maximum pain scores after osmotic dilator placement prior to a dilation and evacuation (D&E) procedure in participants assigned to a prescription for ibuprofen alone or to ibuprofen plus oxycodone.

Study Design: We conducted a nonblinded pragmatic, randomized controlled trial to evaluate pain management among women undergoing osmotic dilator placement prior to D&E. We randomly assigned 70 participants at 12 weeks 6 days to 23 weeks 6 days gestation to receive a prescription for ibuprofen alone, or ibuprofen plus oxycodone.

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Importance: Early pregnancy loss (EPL) is the most common complication of pregnancy. A multicenter randomized clinical trial compared 2 strategies for medical management and found that mifepristone pretreatment is 25% more effective than the standard of care, misoprostol alone. The cost of mifepristone may be a barrier to implementation of the regimen.

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