Publications by authors named "Divya R Santhanam"
Importance: The incidence of infection during SARS-CoV-2 viral waves, the factors associated with infection, and the durability of antibody responses to infection among Canadian adults remain undocumented.
Objective: To assess the cumulative incidence of SARS-CoV-2 infection during the first 2 viral waves in Canada by measuring seropositivity among adults.
Design, Setting, And Participants: The Action to Beat Coronavirus study conducted 2 rounds of an online survey about COVID-19 experience and analyzed immunoglobulin G levels based on participant-collected dried blood spots (DBS) to assess the cumulative incidence of SARS-CoV-2 infection during the first and second viral waves in Canada.
Article Synopsis
- - The study aims to evaluate the effectiveness and tolerability of duloxetine, a non-opioid medication, in treating acute musculoskeletal pain in adults visiting emergency departments, with the goal of preventing chronic pain.
- - Participants will be randomly assigned to receive either 30 mg or 60 mg of duloxetine, or a placebo, and their pain levels and any adverse effects will be monitored over a 6-week period.
- - The research has received ethical approval and findings will be shared through scientific publications and conferences.
Breast cancer is associated with alterations in a number of growth factor and hormone-regulated signaling pathways. Mouse models of metastatic breast cancer typically feature mutated oncoproteins that activate PI3K, Stat3, and Ras signaling, but the individual and combined roles of these pathways in breast cancer progression are poorly understood. In this study, we examined the relationship between oncogenic pathway activation and breast cancer subtype by analyzing mouse mammary tumor formation in which each pathway was activated singly or pairwise.
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