Publications by authors named "Divya N Mallikarjun"
Clinical Manifestations.
Alzheimers Dement
December 2024
Background: Evidence from multiple converging sources has demonstrated the clear benefits of physical activity in promoting mental health and improving cognitive function. However, more than 54% of Indians do not engage in the recommended amount of physical activity. The present study aims to explore the association of physical activity with cognitive abilities among the elderly aging population in an urban Indian setting.
View Article and Find Full Text PDFBackground: Frailty, synonymous with physical vulnerability and decline, may exert nuanced effects on cognitive functions.(Borges, Canevelli, Cesari, & Aprahamian, 2019) This study assesses possible association between frailty and cognitive performance with the aim of identifying vulnerable cognitive domains.
Method: We analysed the baseline data from Tata Longitudinal Study of Ageing (TLSA)(Sundarakumar et al.
Clinical Manifestations.
Alzheimers Dement
December 2024
Background: In the early stages of typical Alzheimer's disease, there is a well-documented pattern of memory deficits, especially episodic memory, substantiated with evidence of medial temporal lobe atrophy, specifically of the hippocampus in line with the memory deficits. Studies have shown that several other demographic, biological, and lifestyle factors influence memory and there is a need for identifying early risk factors and for the development of clinical intervention programs to delay or prevent cognitive decline. Therefore, the objective of this study is to explore the impact of various factors on episodic memory decline in an urban cohort.
View Article and Find Full Text PDFBackground: Pulmonary Function Tests (PFTs) are the non-invasive tests to measure the lung function. Relationship between pulmonary function and cognition is an emerging area of research, understanding this is crucial for prevention and management of dementia. Hence this study aims to investigate the association between pulmonary function and cognition.
View Article and Find Full Text PDFClinical Manifestations.
Alzheimers Dement
December 2024
Background: Auditory attention and memory are the understudied aspects of cognition. Poor performance on cognitive tasks is assumed to be due to peripheral hearing loss, which is not always the case. Auditory processing issues may affect the auditory recall and attention tasks even though the hearing and cognition are normal.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the relationship between homocysteine (HCY) levels, vitamin B12, folic acid, and cognitive impairment across urban and rural populations.
- It analyzes data from two longitudinal studies, revealing that urban participants had higher levels of HCY, vitamin B12, and folic acid compared to their rural counterparts, but no significant difference in these levels between normal and mild cognitive impairment (MCI) cases in the urban cohort.
- While there was no found association between HCY and cognitive status in either cohort, vitamin B12 deficiency was positively linked to cognitive impairment, particularly in the context of higher Clinical Dementia Rating scores.
Background: Examining the distribution of biochemical and haematological tests in different age groups of rural population is necessary to ensure that health care facilities are equipped to address the prevalent health conditions and manage age-related illness effectively. Hence, this study is aimed at seeing the distributions of blood biochemical and haematological parameters in rural population.
Methods: This cross-sectional study investigated the distribution of 26 different haematological and biochemical parameters in longitudinal cohort study (Srinivaspura Aging, NeuoSenescence and COGnition - SANSCOG), from the villages of Srinivaspura, Kolar district, India.