Publications by authors named "Divya Mallam"
We assessed the association of metformin use with survival in colorectal cancer in a population consists mostly of African-American and Afro-Caribbean patients. We identified 585 colorectal cancer patients, 167 (28.6%) and 418 (71.
View Article and Find Full Text PDFCoffee is one of the most commonly consumed beverages in the world. Its health benefits including improved overall survival have been demonstrated in a variety of disease states. To examine the association of coffee consumption with liver disease, a systematic review of studies on the effects of coffee on liver associated laboratory tests, viral hepatitis, nonalcoholic fatty liver disease (NAFLD), cirrhosis and hepatocellular carcinoma (HCC) was performed.
View Article and Find Full Text PDFPatients with breast cancer, which lacks ER, PR, and HER2; "triple negative" (TNBC), are at increased risk of brain metastases (BMs). However, the impact of modern therapy on the risk of BMs and outcomes remains largely unknown. In this retrospective, single-institution study we assessed the incidence of BMs, the therapeutic options, and overall survival, in a recent cohort of patients with TNBC.
View Article and Find Full Text PDFPurpose: Oversuppression of bone turnover can be a critical factor in the pathogenesis of osteonecrosis of the jaw (ONJ). We investigated N-telopeptide of type I collagen (NTX) and bone-specific alkaline phosphatase (BAP) as potential predictors of ONJ onset.
Patients And Methods: Patients with ONJ and available stored serum were identified retrospectively from the institutional databases.
Article Synopsis
- Pregnancy-associated breast cancer (PABC) refers to breast cancer diagnosed during pregnancy or within a year after childbirth, and the study aimed to understand its clinical features and impact on survival compared to non-PABC cases.
- A review of 99 PABC patients found that these cases were more likely to present with negative estrogen and progesterone receptors, advanced tumor stages, and higher grade tumors compared to matched controls.
- Despite these adverse features, the overall survival rates for PABC patients did not differ significantly from controls, suggesting that pregnancy-associated breast cancer itself is not an independent negative prognostic factor when accounting for pathology.