Publications by authors named "Divya Krishna Kumar"
Page 1 of 1
Synopsis of recent research by authors named "Divya Krishna Kumar"
- Divya Krishna Kumar's recent research focuses on the mechanisms of transcription factor (TF) binding and specificity in genomic contexts, particularly exploring how intrinsically disordered regions (IDRs) and various interaction types guide TFs to their binding sites.
- Notable findings reveal that IDRs contain embedded determinants that facilitate the binding and preferences of TFs like Gln3 across different conditions and genomic regions, challenging traditional views on the role of structured motifs.
- Kumar's studies also emphasize the significance of cooperative interactions between multiple TFs on functional promoters and the comparative roles of DNA binding domains versus non-DNA binding sequences in guiding in vivo binding specificity, highlighting complex regulatory architectures in yeast.
