Publications by authors named "Divya G Moodalbail"
Article Synopsis
- Hypertension is a significant risk factor for cardiovascular and renal issues in both children and adults, but its prevalence in children with sickle cell disease (SCD) is not well understood.
- A study of 56 children with SCD revealed that 30% had hypertension, with many cases being masked hypertension discovered through 24-hour ambulatory BP monitoring.
- Identifying hypertension early in these children is crucial, as it can be treated and may help prevent further complications related to cardiovascular and renal health.
Cystic kidney disease includes a wide range of hereditary, developmental, and acquired conditions of the kidneys. Some of the inherited causes of cystic kidney disease include autosomal dominant polycystic kidney diseases (caused by mutations in PKD1 or PKD2), autosomal recessive polycystic kidney disease, tuberous sclerosis complex, von Hippel-Lindau disease, oral-facial-digital syndrome type I, and Hadju-Cheney syndrome. Acquired cystic kidney disease has been reported in patients receiving long-term hemodialysis or peritoneal dialysis and in children after liver transplantation.
View Article and Find Full Text PDFBackground: Chronic kidney disease is strongly linked to neurocognitive deficits in adults and children, but the pathophysiologic processes leading to these deficits remain poorly understood. The NiCK study (Neurocognitive Assessment and Magnetic Resonance Imaging Analysis of Children and Young Adults with Chronic Kidney Disease) seeks to address critical gaps in our understanding of the biological basis for neurologic abnormalities in chronic kidney disease. In this report, we describe the objectives, design, and methods of the NiCK study.
View Article and Find Full Text PDFArticle Synopsis
- CKD (chronic kidney disease) is associated with cognitive deficits and emotional disorders, as supported by various studies focusing on neuroimaging in both children and adults.
- A systematic review was conducted on studies published from 1975 to 2012, finding significant trends such as brain atrophy, vascular issues, and similarities in brain blood flow patterns between CKD patients and those with affective disorders.
- The research emphasizes the role of neuroimaging in understanding how CKD affects brain structure and function over a person's lifetime, suggesting potential benefits for early detection and intervention strategies.