Publications by authors named "Divine Akumo"
Background: Prurigo nodularis (PN) is a rare chronic inflammatory skin disease with a high disease burden, but data on clinical and economic burden are still scarce.
Objective: To describe the real-world epidemiologic, clinical and therapeutic characteristics and related economic burden of patients with PN compared to a benchmark population in Germany.
Methods: This retrospective study was based on an excerpt of German Statutory Health Insurance data of patients with an initial PN diagnosis between 2012 and 2016.
Prurigo nodularis is an itchy skin disease with unknown epidemiology. This study aimed to describe the epidemiology of prurigo nodularis compared with that of psoriasis. The German sickness fund claims database, with 2,783,175 continuously insured patients, included 1,720 patients diagnosed with prurigo nodularis and 51,390 with psoriasis.
View Article and Find Full Text PDFObjectives: To characterize real-world prescribing patterns and their clinical and healthcare resource utilization (HRU) implications in patients with metastatic renal cell carcinoma (mRCC) treated in Germany.
Methods: Eligible individuals were enrolled in the "Bundesverband der Betriebskrankenkassen" claims database and received targeted mRCC therapy between 1 January 2008 and 31 December 2016. Prescribing patterns and HRU were characterized by treatment line and summarized by descriptive statistics.
Article Synopsis
- High productivity of rosmarinic acid (RA) from Orthosiphon aritatus was achieved by using yeast extract and jasmonic acid in in vitro cultures, with yeast extract leading to the highest accumulation.
- LAB fermentation using Lactobacillus species was conducted to investigate the impact of fermentation on antioxidant properties, showing that all fermentation methods reduced RA and total phenolics while slightly increasing flavonoids.
- The extent of RA reduction correlated with higher fermentation duration, particularly notable in liquid state fermentation with L. plantarum at 72 hours, alongside a decrease in overall antioxidant activity, indicating RA's key role in antioxidant properties.
Vitis vinifera c.v. Muscat de Frontignan (grape) contains various high valuable bioactive phenolic compounds with pharmaceutical properties and industrial interest which are not fully exploited.
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