Secondary metabolites from the stem bark of and the seeds of with antibacterial activities.

The methanol stem bark extract of and methanol seed extract of , were subjected to purification using chromatographic techniques. yielded loganic acid (), sweroside () and secoxyloganin (), while afforded , akuammidine (), akuammicine () and alstonine (). The structures of the compounds were elucidated based on their nuclear magnetic resonance (NMR), high-resolution mass spectrometry (HRMS) profiles and comparison with literature data.

and studies reveal antidiabetic properties of arylbenzofurans from the root bark of Stapf.

Diabetes remains an important disease worldwide with about 500 million patients globally. In tropical Africa, is traditionally used in the treatment of diabetes. Biological and phytochemical investigation of the root bark extracts of the plant led to the isolation of a new prenylated arylbenzofuran named 7-(3-hydroxy-3-methylbutyl)moracin M () and two congeners, moracins P () and M ().

Cytotoxic compounds from the leaf of Bersama abyssinica subspecies abyssinica.

From the leaves of Kenyan medicinal plant Bersama abyssinica Subspecies abyssinica, four previously undescribed compounds namely, three bufadienolides, 10β-formylpaulliniogenin B, 10β-formylpaulliniogenin A and 1β-acetoxy-3β,5β-dihydroxy-15-methoxy-16,19-dioxobufa-14(15),20,22-trienolide, and a phenolic compound 2,6,4'-trihydroxybenzophenone-4-O-(6‴-cinnamoyl)-β-D-glucoside were isolated together with four known compounds. The structural elucidation of the compounds was based on 1D and 2D NMR spectroscopy and HRMS data analyses. The relative configurations were defined by NOESY correlations.

Cytotoxic Compounds from the Stem Bark of Two subsp. of .

Three new bufadienolides, namely, paulliniogenin A (), paulliniogenin B (), and 16β-formyloxybersamagenin 1,3,5-orthoacetate (), together with two known bufadienolides and six known phenolic substances, were isolated from the stem bark of subsp. and subsp. .