Background: Application of the nanomaterials to preparing X-ray shields and successfully treating multiresistant microorganisms has attracted great attention in modern life.
Objective: This study aimed to prepare flexible silicone-based matrices containing BiO, PbO, or BiO/PbO nanoparticles and select a cost-effective, cytocompatible, and antibacterial/antifungal X-ray shield in clinical radiography.
Material And Methods: In this experimental study, we prepared the nanoparticles by the modified biosynthesis method and fabricated the X-ray shields containing 20 wt% of the nanoparticles.
Current methods of colon cancer treatment, especially chemotherapy, require new treatment methods due to adverse side effects. One important area of interest in recent years is the use of nanoparticles as drug delivery vehicles since several studies have revealed that they can improve the target specificity of the treatment thus lowering the dosage of the drugs while preserving the effectiveness of the treatment thus reducing the side effects. The use of traditional medicine has also been a favorite topic of interest in recent years in medical research, especially cancer research.
View Article and Find Full Text PDFPolymethyl methacrylate (PMMA) is widely used to manufacture removable orthodontic appliances. However, since the porous structure, cold-curing acrylic resins are susceptible to bacterial adhesion and colonization. The aim of this study was to investigate the antibacterial and mechanical properties of a cold-curing PMMA resin containing ZnO and TiO nanoparticles supported on the 4A zeolite.
View Article and Find Full Text PDFEvid Based Complement Alternat Med
May 2022
Background: The design of new magnetic resonance imaging (MRI) contrast media with chemotherapy drug-carrying capacity has an important role in diagnostic and therapeutic purposes. This study aimed to synthesize a polyethylene glycol (PEG)-coated magnetite/hydroxyapatite nanocomposite as an MRI contrast agent investigate its curcumin loading/release properties and consider the cytotoxicity effect of the curcumin-loaded nanocomposite on different cell lines.
Materials And Methods: PEGylated magnetite/hydroxyapatite (PMHA) nanocomposite was synthesized and characterized using -ray diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy, vibrating sample magnetometry, and energy dispersive -ray analysis.
Introduction: Chitosan is a natural biopolymer that attracted enormous attention in biomedical fields. The main components of regenerative endodontic procedures (REPs), as well as tissue engineering, are scaffolds, stem cells, and growth factors. As one of the basic factors in the REPs is maintaining vascularization, this study was aimed at developing basic fibroblast growth factor- (bFGF-) loaded scaffolds and investigating their effects on the angiogenic induction in human dental pulp stem cells (hDPSCs).
View Article and Find Full Text PDFAlthough doping of various rare earth elements such as samarium on zinc oxide nanoparticles (ZnO NPs) can noticeably improve their photocatalytic performance, it may enhance their toxicity to living organisms. Thus, the toxic impacts of samarium-doped ZnO NPs (Sm/ZnO NPs) on different organisms should be carefully evaluated. In this study, an eco-toxicological experimentation system using the green microalga Chlorella vulgaris was established to determine the potential toxicity of ZnO and Sm/ZnO NPs synthesized by polymer pyrolysis method.
View Article and Find Full Text PDFAim: The objectives of this study were to develop a new bioactive composite resin containing silver/zinc oxide (Ag/ZnO) nanoparticles and investigate the effects on mechanical, cytotoxic, biocompatibility, and antimicrobial properties.
Materials And Methods: Disc-shaped specimens were prepared from composite with and without nanoparticles in separate culture media containing , , and . Bracket bonding evaluation was performed on composite without nanoparticles (O), composite containing ZnO (Z) nanoparticles, composite containing ZnO nanoparticles and silver ions (A&Z), and composite containing Ag/ZnO nanoparticles (AZ) synthesized using optical precipitation.
White spot lesions (WSLs) are one of the adverse effects of fixed orthodontic treatments. They are the primary sign of caries, which means inhibiting this process by antibacterial agents will reverse the procedure. The current study tested the surface modification of nickel-titanium (NiTi) wires with ZnO nanoparticles (NPs), as antimicrobial agents.
View Article and Find Full Text PDFNowadays, vascularization and mineralization of bone defects is the main bottleneck in the bone regeneration field that is needed to be overcome and developed. Here, we prepared novel in-situ formed injectable hydrogels based on chitosan biguanidine and carboxymethylcellulose loaded with vascular endothelial growth factor (VEGF) and recombinant Bone morphogenetic protein 2 (BMP-2) and studied its influence on osteoblastic differentiation of dental pulp stem cells (DPSCs). The sequential release behavior of the VEGF and BMP-2 from hydrogels adjusted with the pattern of normal human bone growth.
View Article and Find Full Text PDFIn this study, three types of Polypropylene-based (PP) films (two active nanocomposites and one control film) containing zinc oxide nanoparticles (ZnO NPs), 4A zeolite (4A Z), and green tea extract (GTE) were studied as modern active packaging's that can adjust the release of antimicrobial agents. The influence of PP nanocomposite with 3% (w/w) ZnO NPs/4A Z/GTE (treatment 1) and 6% (w/w) ZnO NPs/4A Z/GTE (treatment 2) on controlling microbial growth and preserving the sensory and chemical qualities of Salmon over nine days of storage at 4 ± 1°C was evaluated. The disk diffusion test revealed inhibition zones in the range of 10.
View Article and Find Full Text PDFIn this study, nanocomposite films with enhanced functional properties were prepared by loading titanium dioxide (TiO) and/or zinc oxide (ZnO) nanoparticles within 4A zeolite (4AZ) particles, and then incorporating these nanocomposites into a poly (vinyl alcohol) (PVA) and gelatin matrix. The composition and morphology of the films were characterized using atomic force microscopy (AFM), scanning electron microscopy (SEM), Fourier transform infrared (FTIR), and X-ray diffraction (XRD). The thermal behavior of the films was established using thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC).
View Article and Find Full Text PDFJ Biomed Phys Eng
October 2020
Background: Gadolinium oxide nanoparticles as positive contrast material of magnetic resonance imaging (MRI) have attracted a great attention due to the appropriate magnetic properties. One of the most desirable features of these nanoparticles is their ability of doping with other lanthanides which can change their properties.
Objective: This study aimed to investigate the effect of neodymium doping on MRI relaxivity of the gadolinium oxide nanoparticles.
Background: Magnetic resonance imaging (MRI) using nanostructures has been a proper method for tumor targeting purposes. Different MRI nanomaterials, targeting agents and anticancer drugs have been used for targeting of tumors.
Objectives: This study aims to consider the MRI property of doxorubicin (DOX)-loaded gadolinium/13X zeolite/folic acid (Gd/13X/FA) nanocomposite.
In this study, the antimicrobial activity of titanium dioxide (TiO), zinc oxide (ZnO), and TiO/ZnO nanoparticles supported into 4A zeolite (4A z) was assessed. Based on antimicrobial experiments, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), fractional inhibitory concentration (FIC) and disc diffusion test were determined after 24 h of contact with the prepared nanocomposites. These results are in agreements with the results of disc diffusion test.
View Article and Find Full Text PDFRecently, oxo-biodegradable polymers have attracted much attention due to taking less time to break down after disposal in comparison to ordinary polymers. Polyvinyl alcohol/gelatin (PVA/G) nanocomposite films, containing ZnO, TiO or ZnO/TiO nanoparticles supported on 4A zeolite (4A z), are novel active packaging that can control the release of antimicrobial compounds. The present study assessed the efficacy of PVA/G nanocomposite films with 1.
View Article and Find Full Text PDFSnO nanoparticles (NPs) are promising materials for electrochemical, catalytic, and biomedical applications due to their high photosensitivity, suitable stability characteristics, wide band gap energy potential, and low cost. Doping SnO NPs with metallic elements such as Ag has been used to improve their efficiency. Despite their commercial importance, the current literature lacks investigations to determine their toxic effects on plant systems.
View Article and Find Full Text PDFNowadays, distribution and microorganism resistance against antimicrobial compounds have caused crucial food safety problems. Hence, nanotechnology and zeolite are recognized as new approaches to manage this problem due to their inherent antimicrobial activity. Different studies have confirmed antimicrobial effects of Nano particles (NPs) (metal and metal oxide) and zeolite, by using various techniques to determine antimicrobial mechanism.
View Article and Find Full Text PDF. The aim of this in vitro study was to investigate the effect of zinc oxide (ZnO) and zirconium oxide (ZrO) microparticles (MPs) and nanoparticles (NPs) in combination with white Portland cement (WPC) on odontogenic capacity of human dental pulp stem cells over a period of 21 days. .
View Article and Find Full Text PDFStatement Of The Problem: Recently, zeolite has been regarded to improve the properties of dental materials such as mineral trioxide aggregate (MTA).
Purpose: The aim of the present study was to evaluate the effect of incorporating zeolite/silver/zinc (Ze/Ag/Zn) composite at 2 wt% to MTA powder on the push-out bond strength in simulated furcation perforations.
Materials And Method: Furcal perforations, measuring 1.
Background: Magnetic resonance imaging (MRI) contrast agents have an important role to differentiate healthy and diseased tissues. Access and design new contrast agents for the optimal use of MRI are necessary. This study aims to evaluate iron oxide-4A nanocomposite ability to act as a magnetic resonance imaging contrast agent.
View Article and Find Full Text PDFIntroduction: Over the past few decades, the application of nanotechnology has gained progressive interest for the regeneration of injured and burned tissues.
Objective: This study evaluates the effects of titanium dioxide (TiO₂) nanoparticle (NP)/gelatin on burn wound healing in mice.
Materials And Methods: Sixty healthy male BALB/c mice with a full-thickness burn wound were randomized into 4 experimental groups of 15 animals each: (1) control group was treated with normal saline; (2) gelatin group was treated with gelatin-based ointment; (3) silver sulfadiazine group was treated with silver sulfadiazine 1% ointment; and (4) TiO₂ NP/gelatin group (TNG) received TiO₂ NP/gelatin.
Introduction: The aim of this study was to compare the antibacterial effects of two gels containing zinc oxide and zinc oxide/silver nanoparticles and a mixture of calcium hydroxide and 0.12% chlorhexidine as intracanal medicaments in root canals contaminated with () at different time intervals.
Methods And Materials: After preparation and culturing of in 132 single root teeth, the initial count of bacteria was performed.
Background: The aim of this study was to examine and compare the effect of photodynamic therapy and solution containing nano particles Ag/ZnO on adhesion of endodontic sealers to dentinal walls of human root canal.
Material And Methods: Ninty single-rooted human teeth were selected and their clinical crown was cut from the cemento-enamel junction zone. Canals were prepared by RaCe rotary system and the smear layer was removed using 17% EDTA and 5.
Background: This study was carried out to evaluate the biocompatibility of zeolite-silver-zinc (Ze-Ag-Zn) nanoparticles and their effect on the compressive strength of Mineral Trioxide Aggregate (MTA).
Material And Methods: Biocompatibility was evaluated by an MTT assay on the pulmonary adenocarcinoma cells with 0.05, 0.