Need for Advocacy Around Eating Right: A Call for Reducing the Burden of Malnutrition-A Pilot Study.

Background: Adequate nutrition status is imperative for overall health and well-being, although numerous challenges impede its attainment. Various sociodemographic determinants significantly influence an individual's nutrition status, particularly those of women.

Methods: In this pilot study, the dietary patterns of 105 women were collected using the modified version of the FIGO nutrition checklist, along with their sociodemographic details to determine the enablers and barriers to their right nutrition.

A novel pedicle screw design to maximize screw-bone interface strength using finite element analysis and design of experiment techniques.

Study Design: Basic study.

Purpose: This study aimed to utilize finite element (FE) analysis and design of experiment (DoE) techniques to propose and optimize a novel pedicle screw design and compare its pull-out force with that of a control device.

Overview Of Literature: Pedicle screw-based fixation is the gold-standard treatment for spine diseases, particularly in fusion procedures.

Thoracic Dorsal Spinal Cord Herniation: Brief Report and Review of Literature with an Attempt at Hypothesizing the Possible Pathogenesis.

Spontaneous dorsal cord herniations are very rare, with only 3 reported cases published in the literature. We report a case of a 15-year-old girl, presenting with progressive symptoms of myelopathy, diagnosed with dorsal cord herniation. She was managed surgically.

Development of an Evidence-based Care Bundle for Prevention of External Ventricular Drain-related Infection: Results of a Single-center Prospective Cohort Study and Literature Review.

Background: External ventricular drain (EVD)-related infection (ERI) is a common complication in cranial neurosurgery practice with high mortality. The risk factors associated with ERI are not well studied in low- and middle-income countries (LMIC) like India. Identifying the risk variables is a necessity to design robust evidence-based care bundles for ERI prevention.

A prospective observational study to compare and evaluate delta down, aortic velocity time integral variability, and superior vena cava collapsibility index as predictors of fluid responsiveness in patients with supratentorial brain tumors undergoing elective neurosurgery.

Background: Patients undergoing surgical resection of brain tumors frequently exhibit a spectrum of hemodynamic fluctuations necessitating careful fluid management. This study aimed to evaluate the feasibility of dynamic predictors of fluid responsiveness, such as delta down (DD), aortic velocity time integral variability (VTIAoV), and superior vena cava collapsibility index (SVCCI), in patients undergoing neurosurgery for brain tumors.

Methods: In this prospective study, 30 patients scheduled to undergo elective neurosurgery for brain tumor resection were enrolled.

Role of Multimodal Monitoring in the Management of Massive Blood Transfusion in Pediatric Patients Undergoing Excision of Choroid Plexus Carcinoma - A Case-Based Review of a Novel Perioperative Protocol.

Choroid plexus carcinomas (CPCs) are rare intraventricular lesions encountered in the pediatric population. The dreaded perioperative complication causing high mortality and morbidity in patients undergoing excision of CPC is massive intraoperative hemorrhage, which results in massive blood transfusion, and coagulopathy. Hence, the main crux of perioperative management is to tackle intraoperative hemorrhage and coagulopathy by instituting goal-directed blood transfusion guided by multimodality monitoring.

Epidemiology, clinical profile, and outcomes of CSF-diversion catheter-related infections - Prospective cohort study results from a single quaternary neurosurgery referral centre.

Background: Device-associated CNS infections is a major subgroup of healthcare associated CNS infections. Healthcare-associated ventriculitis or meningitis differs considerably from community-acquired meningitis in its epidemiology, pathogenesis, clinical presentation and management.

Objectives: This study aimed to identify the infection rates, the associated risk factors, and outcomes of these life-threatening infections.

Colloid Cyst: Revision of Third Ventricular Zones for Risk Stratification of Hydrocephalus.

Objective: We sought to reclassify the "anatomic risk zones of colloid cysts" as proposed by Beaumont et al, by proposing newer landmarks, and to assess predictive value for the risk of occurrence of hydrocephalus with the new classification compared with the old.

Methods: A retrospective cohort of 122 cases of colloid cyst of third ventricle were categorized into zones 1, 2, or 3 based on Beaumont's classification (old zone) and our classification (new zone) based on radiologic images. We attempted to recategorize these zones by assigning new anatomic landmarks.

Assessment and Evaluation of Soft Tissue Measurements between Various Mandibular Divergences in the South Indian Population: A Cephalometric Study.

Aim: The aim of this study is to evaluate the association between the mandibular divergent patterns and soft tissue chin (STC) thickness measured at different chin levels in nongrowing patients.

Methodology: Pretreatment lateral cephalograms of 400 adult patients were segregated into four groups based on mandibular divergence pattern defined by the mandibular plane to cranial base angle (average 32° ± 5°), Group I with low angle (below 27°), Group II with medium low angle (28°-32°), Group III with medium high angle (33°-36°), and Group IV with high angle (above 37°). STC thickness was measured between Pog-Pog' (pogonion), Gn-Gn' (gnathion), and Me-Me' (menton), thickness and height of the upper and lower lips were also measured.

Computation and Collation of Torque Expression in 0.018 Inch and 0.022 Inch Preadjusted Bracket Slots on Passive Insertion of Full-Size Archwire: A Finite Element Study.

Aim: To quantify and compare the prescribed torque expressed in preadjusted edgewise 0.018-inch and 0.022-inch bracket slot on passive insertion of full-size archwire using finite element method.

Assessing the Validity and Reliability of Tooth Widths and Bolton Ratios Obtained from Digital Models and Plaster Models.

Aim: The aim of the study is to compare and evaluate the validity and reliability of tooth widths and Bolton ratios measured from digital models obtained from intraoral scanners and plaster models derived from alginate and polyvinyl siloxane impression materials.

Materials And Methods: Alginate and polyvinylsiloxane impression was taken for 40 subjects, orthokal stone was poured and grouped as Group I and Group II, respectively. Intraoral scanning was done using Trios Pod 3shape for the same patients, digital models were obtained and grouped as Group III.

An Experimental Study on Esthetic Preference and Satisfaction of Lip Position with Various Facial Divergences among the South Indian Population.

Aim: The aim of this study was to establish the most and least pleasing lip position and to evaluate esthetic preference in profile view among the South Indian population with diverse facial divergence.

Materials And Methods: Photographs of 12 participants with an average lip position were taken, and original lip position (Image C) was altered by ± 2 mm and ± 4 mm from the original position of upper and lower lips using Adobe Photoshop 7.0 version.

Complex split cord malformation with split conus.

Split cord malformations are disorders of gastrulation. Disorders of secondary neurulation occur later and are traditionally considered separate from the former. Complex split cord malformations involving both the cord and the conus and encompassing the epochs of gastrulation, primary neurulation, junctional neurulation, and secondary neurulation have not been described in literature.

Compressive vertebral hemangiomas with neurological deficits: diagnosis, surgical strategies and long term outcome.

Purpose: Compressive vertebral hemangiomas with neurological deficits (CVHND) form a rare, unique subset of lesions comprising of differing clinico-imaging findings, pathologic behavior and treatment, when compared to the commoner and usually incidental intra-osseus vertebral hemangiomas (VH). Though various surgical strategies and a broad array of adjuncts have evolved and changed over the years, there is paucity of comprehensive data from sizeable series of such patients treated surgically with long term follow up. The purpose of this study is to device an optimum management strategy in CVHND based on our surgical experience.

Split Cord Malformation Type 2 with Double Dorsal Lipoma: A Sequela or a Chance.

An 11-month-old baby girl, with normal perinatal history, presented with a congenital lumbosacral swelling and a sacral dimple. Imaging revealed a split cord malformation (SCM) type 2 at L1-L3 with a lipomeningocoele extending intradurally and tethering both the hemicords, the conus was noted to be at L4. She underwent excision of the lipoma and detethering of the hemicords.

Spinal angiolipoma-a rare but reversible cause of paraplegia in a child.

Purpose: Spinal angiolipomas are benign spinal epidural tumors consisting of mature fat cells with angiomatous components. These tumors are rare in children and there are no definite management guidelines.

Method: To the best of our knowledge, only five cases of spinal angiolipomas have been reported in children below 12 years.

Enhanced Water Dispersibility of Curcumin Encapsulated in Alginate-Polysorbate 80 Nano Particles and Bioavailability in Healthy Human Volunteers.

Background: The turmeric (Curcuma longa) plant, a perennial herb of the ginger family, is an agronomic crop in the south and southeast tropical Asia. Turmeric an Indian yellow gold and universal spice is described in Ayurveda, an ancient treatise on longevity and quality life for the treatment of various inflammatory disorders. The oral bioavailability of curcumin is low due to poor aqueous solubility, alkaline instability and speedy elimination.

Synthesis pharmacological evaluation and docking studies of pyrimidine derivatives.

A new group of pyrimidine derivatives of indane-1,3-dione were synthesized aiming at the synthesis of new compounds acting as analgesic, anti-inflammatory and antimicrobial activity in a single component. The title compounds (3a-l) were synthesized from chalcone derivatives of indane-1,3-dione (2a-l) through cyclization reaction with urea. The synthesized compounds were characterized by FT-IR, (1)H NMR, mass spectral data, elemental analysis and evaluated for anti-inflammatory, analgesic, antibacterial and antifungal activities.

Formulation development and rheological studies of palatable cefetamet pivoxil hydrochloride dry powder suspension.

Background And The Purpose Of The Study: Because of its intense bitter taste and susceptibility to moisture Cefetamet Pivoxil (CPH) is presently available only in the form of tablet. The aim of this study was to develop taste masked CPH dry powder suspension.

Methods: METHODS EMPLOYED FOR FORMULATIONS WERE: a) Film coating of CPH using Eudragit E100 and subsequent adsorption on different carriers such as spray-dried lactose, sodium starch glycolate and spray-dried mannitol and b) Complexation of CPH with three different ion exchange resins indion 234 amberlite IRP64 and amberlite IRP69.

Protective effect of the hydro-alcoholic extract of Rubia cordifolia roots against ethylene glycol induced urolithiasis in rats.

Unlabelled: This study investigated the protective effect of the hydro-alcoholic extract of roots of Rubia cordifolia Linn. (HARC) against ethylene glycol induced urolithiasis and its possible underlying mechanisms using male Wistar albino rats. Ethylene glycol feeding resulted in hyperoxaluria, hypocalciuria as well as increased renal excretion of phosphate.