Publications by authors named "Ditte Georgina Zhang"
Plasma proteomics analysis of patients with chronic spontaneous urticaria reveals significant associations with key disease characteristics but not with response to omalizumab treatment.
Allergy
September 2024
Introduction: Pre-graduate research is popular among medical students. Concerns about time constraints and lack of mentorship have been raised in international studies. The extent to which these issues affect Danish medical students remains unclear.
View Article and Find Full Text PDFIntroduction: The internet is a popular source of health information including images of disease manifestations. Online photographs of skin lesions may aid patients in identifying their disease, if these pictures are of good quality and of the disease they claim to show. If not, patients may be at risk of delayed diagnosis, misdiagnosis, and suboptimal treatment.
View Article and Find Full Text PDFArticle Synopsis
- Chronic urticaria (CU) involves symptoms like wheals and angioedema that may not be visible during medical visits, leading to challenges in diagnosis.
- A study assessed the effectiveness of smartphone photos taken by CU patients before their first clinic appointment, focusing on photo quality and usefulness for physicians.
- Findings revealed that a significant number of patients (79.7%) took photos, mostly of wheals, and the majority (86%) of these photos were deemed useful for clinical evaluation, indicating that self-captured images can aid in diagnosis.
Chronic urticaria (CU) is a debilitating skin disease affecting around 1% of the population. CU can be subdivided into chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU). Different pathophysiological mechanisms have been proposed to play a role in the development of CU, and these are also being investigated as potential biomarkers in the diagnosis and management of the disease.
View Article and Find Full Text PDFBackground: Chronic urticaria (CU) has been associated with several systemic and autoimmune disorders. The association with atopic disorders is however controversial. The objective of this study was to perform a systematic review and meta-analysis to assess the association between CU and the atopic disorders: atopic dermatitis (AD), asthma, and allergic rhinoconjunctivitis (ARC).
View Article and Find Full Text PDFBackground: The pathogenesis of rosacea is incompletely understood. Signaling neuropeptides, including PACAP, a regulator of vasodilation and edema, are upregulated in rosacea skin. Here, we evaluated PACAP38-induced rosacea features and examined whether a 5-HT receptor agonist could reduce these features.
View Article and Find Full Text PDFObjective: To determine whether early treatment with sumatriptan can prevent PACAP38-induced migraine attacks.
Methods: A total of 37 patients with migraine without aura were enrolled between July 2018 to December 2019. All patients received an intravenous infusion of 10 picomole/kg/min of PACAP38 over 20 min followed by an intravenous infusion of 4 mg sumatriptan or placebo over 10 min on two study days in a randomised, double-blind, placebo-controlled, crossover study.
Purpose: Migraine has consistently been connected with rosacea. Commonalities in epidemiology, trigger factors and associated neuropeptides support shared aetiology and pathophysiological pathways, though underlying mechanisms remain unclear. We established two cohorts of patients diagnosed with either migraine and/or rosacea.
View Article and Find Full Text PDFObjective: To investigate plasma glucose changes during the ictal state of migraine compared to the interictal state.
Background: Previous studies suggest abnormal glucose metabolism in migraine patients during and outside of attacks. It is not known if plasma glucose levels change during spontaneous migraine attacks.