Publications by authors named "Dirk W Dressler"
Article Synopsis
- A study aimed to evaluate changes in the neurometabolic profile of early-stage Parkinson's disease (PD) patients using whole brain magnetic resonance spectroscopic imaging (wbMRSI) as a potential early diagnostic tool.
- The research involved 20 PD patients and 20 healthy controls, measuring brain metabolite concentrations across various lobes, revealing significant decreases in specific metabolites in the brain areas opposite the more affected side of the body.
- Findings suggest that metabolic changes in early PD indicate broader neurodegenerative impacts throughout brain networks, highlighting wbMRSI's potential as a biomarker for early diagnosis and monitoring of the disease.*
Background: Parkinson's disease (PD) is the second most frequent neurodegenerative disease of the elderly. Patients suffer from various motor and non-motor symptoms leading to reduced health-related quality of life (HRQOL) and an increased mortality. Their loss of autonomy due to dementia, psychosis, depression, motor impairments, falls, and swallowing deficits defines a phase when palliative care interventions might help to sustain or even improve quality of life.
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