High-resolution analysis of individual larvae uncovers individual variability in locomotion and its neurogenetic modulation.

Neuronally orchestrated muscular movement and locomotion are defining faculties of multicellular animals. Due to its simple brain and genetic accessibility, the larva of the fruit fly allows one to study these processes at tractable levels of complexity. However, although the faculty of locomotion clearly pertains to the individual, most studies of locomotion in larvae use measurements aggregated across animals, or animals tested one by one, an extravagance for larger-scale analyses.

Insight Beyond Numbers: The Impact of Qualitative Factors on Visual Data Analysis.

As of today, data analysis focuses primarily on the findings to be made inside the data and concentrates less on how those findings relate to the domain of investigation. Contemporary visualization as a field of research shows a strong tendency to adopt this data-centrism. Despite their decisive influence on the analysis result, qualitative aspects of the analysis process such as the structure, soundness, and complexity of the applied reasoning strategy are rarely discussed explicitly.

Understanding a Sequence of Sequences: Visual Exploration of Categorical States in Lake Sediment Cores.

This design study focuses on the analysis of a time sequence of categorical sequences. Such data is relevant for the geoscientific research field of landscape and climate development. It results from microscopic analysis of lake sediment cores.

The LloydRelaxer: An Approach to Minimize Scaling Effects for Multivariate Projections.

Star Coordinates are a popular projection technique in order to analyze and to disclose characteristic patterns of multidimensional data. Unfortunately, the shape, appearance, and distribution of such patterns are strongly affected by the given scaling of the data and can mislead the projection-based data analysis. In an extreme case, patterns might be more related to the choice of scaling than to the data themselves.

Optimal Sets of Projections of High-Dimensional Data.

Finding good projections of n-dimensional datasets into a 2D visualization domain is one of the most important problems in Information Visualization. Users are interested in getting maximal insight into the data by exploring a minimal number of projections. However, if the number is too small or improper projections are used, then important data patterns might be overlooked.

Blood Flow Clustering and Applications in Virtual Stenting of Intracranial Aneurysms.

Understanding the hemodynamics of blood flow in vascular pathologies such as intracranial aneurysms is essential for both their diagnosis and treatment. Computational fluid dynamics (CFD) simulations of blood flow based on patient-individual data are performed to better understand aneurysm initiation and progression and more recently, for predicting treatment success. In virtual stenting, a flow-diverting mesh tube (stent) is modeled inside the reconstructed vasculature and integrated in the simulation.

Orthographic star coordinates.

Star coordinates is a popular projection technique from an nD data space to a 2D/3D visualization domain. It is defined by setting n coordinate axes in the visualization domain. Since it generally defines an affine projection, strong distortions can occur: an nD sphere can be mapped to an ellipse of arbitrary size and aspect ratio.

Results in the long-term course after stapled transanal rectal resection (STARR).

Purpose: Stapled transanal rectal resection (STARR) has recently been recommended for patients with obstructed defecation caused by rectocele and rectal wall intussusception. Our study investigates the long-term results and predictive factors for outcome.

Methods: Between November 2002 and February 2007, 80 patients (69 females) were operated on using the STARR procedure and included in the following study.

Features in Continuous Parallel Coordinates.

Continuous Parallel Coordinates (CPC) are a contemporary visualization technique in order to combine several scalar fields, given over a common domain. They facilitate a continuous view for parallel coordinates by considering a smooth scalar field instead of a finite number of straight lines. We show that there are feature curves in CPC which appear to be the dominant structures of a CPC.

Discontinuities in continuous scatter plots.

The concept of continuous scatterplot (CSP) is a modern visualization technique. The idea is to define a scalar density value based on the map between an n-dimensional spatial domain and an m-dimensional data domain, which describe the CSP space. Usually the data domain is two-dimensional to visually convey the underlying, density coded, data.

Surgical trauma affects the proinflammatory status after cardiac surgery to a higher degree than cardiopulmonary bypass.

Objectives: Cytokines contribute to the development of the systemic inflammatory response syndrome or multiple-organ failure frequently observed after cardiopulmonary bypass-supported cardiac surgery. To quantify the contribution of bypass-induced versus trauma-induced inflammatory response after coronary artery bypass grafting, we examined plasma cytokine levels in 120 patients with coronary artery disease who were treated with or without cardiopulmonary bypass-assisted procedures.

Methods: Patients were treated in accordance with one of the following protocols: (1) elective percutaneous coronary intervention without cardiopulmonary bypass (n = 69), (2) cardiopulmonary bypass-supported percutaneous coronary intervention (cardiopulmonary bypass-percutaneous coronary intervention; n = 10), and (3) cardiopulmonary bypass-supported coronary artery bypass grafting (cardiopulmonary bypass-coronary artery bypass grafting; n = 41).