Publications by authors named "Dirk Hendrik Nicolaas van den Broek"
Article Synopsis
- This study investigates the impact of a magnesium-enriched diet on cats with chronic kidney disease (CKD), focusing on its potential to improve plasma magnesium levels and overall health outcomes.* -
- Sixty client-owned cats with CKD were randomly split into two groups: one received a magnesium-enriched phosphate-restricted diet (PRD), while the other received a standard PRD. Results showed an increase in total magnesium in the magnesium group without negative side effects.* -
- The magnesium-enriched diet led to better management of CKD-related issues, such as lower trends in ionized calcium levels and stable fibroblast growth factor-23 concentrations, suggesting this dietary modification could be beneficial for feline patients with CKD.*
Background: Microscopic nephrocalcinosis is a common pathological feature of chronic kidney disease (CKD) in cats. Detection of macroscopic nephrocalcinosis using ultrasonography and its implications remain unexplored.
Objectives: Identify risk factors associated with ultrasound-diagnosed nephrocalcinosis and evaluate the influence of nephrocalcinosis on CKD progression.
Article Synopsis
- This study investigates how effectively ultrasonography detects nephrocalcinosis in cats with chronic kidney disease (CKD) by comparing it with micro-computed tomography and histopathology techniques.* -
- Twelve kidneys from seven client-owned cats with CKD were examined, revealing that ultrasonography classified kidneys into three categories: absent, suspected, and present for nephrocalcinosis.* -
- The results showed a strong correlation between macroscopic and microscopic assessments of nephrocalcinosis, suggesting that while ultrasonography may provide some insights, advanced imaging and histological methods are crucial for accurate detection.*
Background: Hypercalcemia is associated with chronic kidney disease (CKD) in cats, but studies assessing the physiologically relevant ionized calcium fraction are lacking.
Objectives: To describe the prevalence and incidence rate of ionized hypercalcemia, and to explore predictor variables to identify cats at risk of ionized hypercalcemia in a cohort of cats diagnosed with azotemic CKD.
Animals: One hundred sixty-four client-owned cats with azotemic CKD.