Background: It has been shown that ventilation-induced pulse pressure variation (PPV) is a better variable than central venous pressure (CVP) or pulmonary artery occlusion pressure (PAOP) for predicting cardiac output changes after fluid administration. The plethysmographic wave form measured with a fingertip pulse is very similar to the arterial blood pressure curve.
Methods: We investigated whether this widely used, noninvasive instrument could predict fluid responsiveness by conducting an observational study in 32 patients who had undergone cardiac surgery.