Publications by authors named "Dirican A"

Background: Epignathus is a rare kind of teratoma. Its estimated incidence is one in 35,000-200,000 live births, and it may cause high mortality by causing airway obstruction in the neonatal period. It is generally diagnosed in the prenatal period.

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  • * Among 106 patients, 83 had CN, and those who had the surgery could continue their nivolumab treatment for longer (14.5 months) compared to those who didn't have the surgery (6.7 months).
  • * Overall survival was better for patients with CN (22.9 months) compared to those without it (8.1 months), but the surgery and certain medical scores were important factors for how long they lived.
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Objective: It was aimed to examine the overall role of cold ischemia time and anhepatic phase durations in terms of peroperative blood transfusion needs, hospital stay conditions and postoperative charges, and survival in recipients.

Material And Methods: One hundred forty-eight adult living donor liver transplant recipients (18 years and older) were included in the study. Whether the anhepatic phase and cold ischemia duration have an effect on the rates of surgery time, blood product transfusion, total hospital and intensive care unit stay, postoperative biliary complications, hepatic vein thrombosis, portal vein thrombosis, early postoperative bleeding, sepsis, and primary graft dysfunction.

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Background: The research was conducted to evaluate the birth and newborn outcomes of Syrian immigrant women according to maternal age groups and Vitamin D use.

Methods: It was conducted retrospectively using the birth records of 2,866 Syrian migrant women, who had given birth at a tertiary center between January 2016 and May 2020. Demographic features, obstetric and neonatal outcomes were analyzed according to age groups and Vitamin D use.

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Background: Hepatocellular carcinoma (HCC) is a significant health problem, and the associated mortality rate is increasing.

Aim: We aimed to determine the clinical characteristics and prognosis for HCC in member countries of the OncoBridge Study Group.

Methods: We recruited 630 patients diagnosed with HCC between 2013 and 2019 from 4 countries (Türkiye, Russia, Georgia, and Greece).

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Objective: To assess the quality of information presented in YouTube videos about human papillomavirus vaccination.

Methods: The descriptive study was conducted at Konya Meram Education and Research Hospital, On October 15, 2019 when the YouTube website was search using the terms 'human papillomavirus', 'HPV vaccine' and 'Gardasil'. The vide-os were recorded to a playlist by two individual gynaecologists to prevent any change in the listed videos.

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A 42-year-old female patient diagnosed with invasive ductal breast ca underwent F-fluorodeoxyglucose (FDG) positron emission tomography/ computed tomography (PET/CT) scan for staging, 1.5 cm diameter hypermetabolic lesion was observed in the lower inner quadrant of the right breast that was compatible with primary tumor [maximum standardized uptake value (SUV): 10.5].

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Drawing upon conservation of resources and social bonding theories, the present study examined the associations between job embeddedness and employee work behaviors (altruism and organizational deviance) by exploring the moderating role of leader-member exchange (LMX) in these associations. Using a cross-sectional research design, data were collected from a sample of 637 employees in Turkey. The data were analyzed using confirmatory factor analysis, structural equation modeling, and bootstrapping.

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: Drawing upon the identity disruption model, we investigated the association between child abuse experiences (emotional, physical, and sexual) and intolerance of uncertainty. We also addressed demographic differences in uncertainty intolerance in this study. : Using online survey questionnaires, we collected data from a sample of 302 young adults in Turkey.

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Background: Living donor liver transplantation (LDLT) has become an increasingly common surgical option because the number of cadaveric donors is insufficient to fulfill the organ needs of patients facing end-stage cirrhosis. Many centers are investigating different surgical techniques to achieve lower complication rates. We aimed to examine our complication rates in light of demographic data, graft data, and perioperative findings as a single-center experience.

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Introduction: In oral and maxillofacial surgery, hard tissue augmentation is provided by materials that accelerate the healing, act as a template for reconstructing bony defects, and stimulate bone production and growth. This study investigated the effects of biocompatible carriers containing active vitamin D and platelet-rich plasma (PRP) on bone defects created in rat calvaria.

Material And Methods: This experimental animal study utilized fifty-two male Sprague Dawley rats divided into six groups and conducted histopathological, microtomographic, and biochemical comparisons by adding vitamin D, which has an accelerating effect on bone development.

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Skin diseases are commonly treated with antihistamines, antibiotics, laser therapy, topical medications, local vitamins, or steroids. Since conventional treatments for wound healing (skin allografts, amnion, xenografts, etc.) have disadvantages such as antigenicity of the donor tissue, risk of infection, or lack of basement membrane, skin tissue engineering has become a popular new approach.

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Background: Our objective was to determine the levels of heavy metals, oxidants, and antioxidants in liver tissue of patients with chronic liver disease (CLD) compared with healthy living liver donors (LLDs).

Methods: We obtained liver specimens from patients undergoing liver transplant for CLD. Samples were also obtained from LLDs.

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Objective: In this retrospective study, we compared the postoperative complications by using both the Clavien-Dindo classification and the Revised 2016 International Study Group on Pancreatic Surgery (ISGPS) classification methods after pancreaticoduodenectomy.

Materials And Methods: The data of patients were retrospectively reviewed. Pancreaticojejunostomy (PJ) and pancreaticogastrostomy (PG) were performed on 41 and 40 patients, respectively.

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Objective: The main purpose of our study is to analyze the predictive and prognostic value of inflammatory prognostic index (IPI (using albumin, CRP, neutrophils and lymphocytes) and albumin / bilirubin ratio in metastatic pancreatic cancer patients in addition to other markers currently used.

Materials And Methods: Medical records of patients with pancreatic cancer treated in Celal Bayar University Medical Faculty Hospital Medical Oncology Clinic between February 2012 and April 2020 were retrospectively reviewed. Clinicopathologic variables such as age, gender, performance status (PS), treatments, histopathology type, localization of metastasis, comorbidity were recorded by an electronic medical record system.

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Introduction: We aimed to evaluate clinical and laboratory findings of hospitalized asthma and chronic obstructive pulmonary disease (COPD) patients with COVID-19 and demonstrate that they have different symptoms and/or laboratory results and outcomes than COVID-19 patients with comorbidity (CoV-com) and without comorbidity (CoV-alone).

Methodology: The data of the demographic, clinical, laboratory findings of hospitalized CoV-alone, asthma, COPD patients with COVID-19 (CoV-asthma, CoV-COPD, respectively), and CoV-com were analyzed.

Results: Out of 1082 patients hospitalized for COVID-19, 585 (54.

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Article Synopsis
  • Scientists studied how proteins called heat shock proteins (HSPs) relate to a kidney problem called chronic kidney disease (CKD) in children.
  • They looked at 117 kids with CKD and 56 healthy kids over two years to see how HSP levels changed in their urine and blood.
  • The study found that while certain HSP levels got lower over time in CKD kids, some levels increased, which may mean HSPs don't help as much in protecting against CKD as they should.
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Background: Acromegaly is a disease that occurs as a result of excessive growth hormone caused by pituitary adenomas. Some acromegaly patients show resistance to somatostatin analog (SSA) treatment. Filamin-A (FLNA) and β-arrestins are thought to play a role in the response to SSAs.

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Background: Although the detection of viral particles by reverse transcription polymerase chain reaction (RT-PCR) is the gold standard diagnostic test for coronavirus disease 2019 (COVID-19), the false-negative results constitute a big challenge.

Aim: To examine a group of patients diagnosed and treated as possible COVID-19 pneumonia whose multiple nasopharyngeal swab samples were negative for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by RT-PCR but then serological immunoglobulin M/immunoglobulin G (IgM/IgG) antibody against SARS-CoV-2 were detected by rapid antibody test.

Methods: Eighty possible COVID-19 patients who had at least two negative consecutive COVID-19 RT-PCR test and were subjected to serological rapid antibody test were evaluated in this study.

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Objective: COVID-19 may yield a variety of clinical pictures, differing from pneumonitis to Acute Respiratory Distress Syndrome along with vascular damage in the lung tissue, named endotheliitis. To date, no specific treatment strategy was approved for the prevention or treatment of COVID-19 in terms of endotheliitis-related comorbidities. Here, we presented our treatment strategies for 11 190 COVID-19 patients depending on categorisation by the severity of both the respiratory and vascular distress and presented the manifestations of endotheliitis in skin, lung and brain tissues according to the different phases of COVID-19.

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This study aimed to demonstrate the efficacy of our diagnostic and therapeutic management algorithm and catheter-assisted (percutaneous transhepatic biliary tract drainage [PTBD] or transanastomotic feeding tube) hepaticojejunostomy (HJ) procedures in living liver donors (LLDs) with biliary complications. Living donor hepatectomy (LDH) was performed between September 2005 and April 2021 in 2 489 LLDs. Biliary complications developed in 220 LLDs (8.

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Aim: We classified anatomical localisation tumours of patients diagnosed with colorectal cancer and undergoing surgery as right and left colon and we aimed to determine how this funding affects the prognosis of the disease and survival times.

Methods: In our study, 521 patients who applied to the general surgery outpatient clinic of İnönü University Turgut Özal Medical Center 19.06.

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Article Synopsis
  • The study investigates the effectiveness of corticosteroid treatment in COVID-19 pneumonia patients who do not have acute respiratory distress syndrome or septic shock, aiming to clarify its benefits during both the activation and recovery phases of the illness.
  • A total of 47 patients were analyzed, with findings indicating that corticosteroid use led to significant reductions in inflammatory markers and improved clinical symptoms, especially in the recovery phase.
  • Results showed that while both groups experienced improvements, the recovery group had better outcomes in terms of complete symptomatic and radiological improvement compared to those treated during the activation phase.
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  • The study looked at how well a drug called Atezolizumab (ATZ) worked for patients with a tough type of cancer that didn't respond to earlier treatment.*
  • Researchers checked the health data of 113 patients to find out which factors might affect how long they lived after taking ATZ.*
  • Important factors that seemed to be linked to shorter survival included having liver metastases, poor overall health, and low hemoglobin levels.*
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Purpose: To investigate the clinical importance of the inflammatory prognostic index (IPI) in patients with metastatic colorectal cancer treated with regorafenib.

Methods: A retrospective analysis of 65 metastatic CRC patients treated with regorafenib between 2015 and 2020 was performed. The association between NLR, PNLR, IPI, and overall survival (OS) and progression-free survival (PFS) was evaluated.

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