Impact of Cold Therapy on Paclitaxel-Induced Peripheral Neuropathy and Quality of Life in Patients With Breast Cancer.

Background: Taxane drugs frequently produce peripheral neuropathy (PN). Cold therapy to hands and feet during chemotherapy has been effective in reducing PN.

Objectives: The purpose was to compare the frequency and severity of PN and quality of life in patients with breast cancer receiving cold therapy to their hands and feet versus standard of care during 12 weekly paclitaxel infusions with a follow-up at 16 weeks.

Assessing Predictors of Emotional Distress by Immigrant Type: An Exploration of Adult Refugees, Asylees, and SIV Holders in Maryland.

Stressors and trauma experienced by persons fleeing harm or persecution can cause elevated distress. This study assessed predictors of elevated distress among newly arrived refugees, asylees, and Special Immigrant Visa (SIV) holders in Maryland. A secondary analysis of Refugee Health Screener-15 data from 4385 refugees, asylees, and SIV holders arriving in Maryland from 2014 to 2017 was conducted.

Simultaneous determination of borate, chloride and molybdate in pyrohydrolysis distillates of plant and soil samples by ion chromatography.

Determination of concentrations of micronutrients in plant samples is important in order to assess the growth and quality of plants. An ion chromatography (IC) method was developed for the simultaneous determination of B, Cl and Mo (micronutrients present in their anionic form in aqueous samples) using a gradient elution with d-mannitol and NaOH. Despite their different chemical nature, these elements could be separated from the matrix by employing pyrohydrolysis.

Discovery and Subsequent Confirmation of Novel Serum Biomarkers Diagnosing Alzheimer's Disease.

Background: Alzheimer's disease (AD) remains challenging to diagnose, especially early disease. Having serum AD biomarkers would be of significant interest both in the clinical setting and in drug development efforts.

Objective: We applied a novel serum proteomic approach to interrogate the low-molecular weight proteome for serum AD biomarkers.

Direct Separation of Molybdenum from Solid Uranium Matrices Employing Pyrohydrolysis, a Green Separation Method, and Its Determination by Ion Chromatography.

Pyrohydrolysis is a well-established separation method, and it is being used as a sample preparation method for several materials for further determination of non-metals such as halogens, boron, and sulfur. Analytes are retained in a diluted solution that is suitable for carrying out analysis by several determination techniques and minimizing the use of concentrated reagents. Pyrohydrolysis separation of metals has not been reported yet.

Antepartum Mastitis: A Rare Occurrence.

Puerperal or lactational mastitis is an inflammatory condition of the breast that is commonly encountered in breastfeeding mothers. It occurs most commonly in the postpartum period, generally in the first 6 weeks of breastfeeding. In contrast, antepartum mastitis is an uncommon condition, and if not treated adequately, it may be complicated by the formation of a breast abscess.

Separation of boron from borated paraffin wax by pyrohydrolysis and alkali extraction methods and its determination using ion chromatography.

A method based on the pyrohydrolysis extraction of boron and its quantification with ion chromatography was proposed for paraffin waxes borated with H3BO3 and B4C. The optimum pyrohydrolysis conditions were identified. Wax samples were mixed with U3O8, which prevents the sample from flare up, and also accelerates the extraction of boron.

Comparing the effect of a resin based sealer on crown retention for three types of cements: an in vitro study.

To determine the effect of resin based sealer on retention of casting cemented with three different luting agents. 55 extracted molar teeth were prepared with a flat occlusal surface, 20° taper and 4 mm axial height. The axial surface of each specimen was determined.

Tissue proteomics of the low-molecular weight proteome using an integrated cLC-ESI-QTOFMS approach.

Analysis of the protein/peptide composition of tissue has provided meaningful insights into tissue biology and even disease mechanisms. However, little has been published regarding top down methods to investigate lower molecular weight (MW) (500-5000 Da) species in tissue. Here, we evaluate a tissue proteomics approach involving tissue homogenization followed by depletion of large proteins and then cLC-MS (where c stands for capillary) analysis to interrogate the low MW/low abundance tissue proteome.

An in-vitro evaluation of the flexural strength of heat-polymerized poly (methyl methacrylate) denture resin reinforced with fibers.

Fracture strength of denture base resins is of great concern and many approaches have been made to improve the fracture resistance of acrylic resin dentures by strengthening them. Purpose of the study was to assess the effect of a Novel pre-impregnated glass fiber reinforcement system and nylon fiber reinforcement on the flexural strength of conventional heat-polymerized poly(methylmethacrylate) [PMMA] denture resin under dry and wet storage conditions. Forty specimens of standard dimensions were prepared for each of the four experimental groups; unreinforced conventional acrylic resin and the same reinforced with unidirectional Stick (S) glass fibers, woven Stick Net (SN) glass fibers and nylon fibers.

Risk factors for sporadic cryptosporidiosis among immunocompetent persons in the United States from 1999 to 2001.

Many studies have evaluated the role of Cryptosporidium spp. in outbreaks of enteric illness, but few studies have evaluated sporadic cryptosporidiosis in the United States. To assess the risk factors for sporadic cryptosporidiosis among immunocompetent persons, a matched case-control study was conducted in seven sites of the Foodborne Diseases Active Surveillance Network (FoodNet) involving 282 persons with laboratory-identified cryptosporidiosis and 490 age-matched and geographically matched controls.

Impediment profiling for smoking cessation. Preliminary experience.

Introduction: Cigarette smoking is a leading cause of preventable death.

Methods: Long and short "impediment profilers" (LIPs and SIPs, respectively) addressing nicotine addiction, depression, anxiety, stress, chemical dependency, weight control, and household smoking were developed and applied in a pilot smoking cessation study to tailor treatment.

Results: Quit rate 72 hours after the target quit date was 50%; at 8 and 12 weeks it was 61% and 39%, respectively.

Impediment profiling for smoking cessation: results of a pilot study.

Objective: To test the effectiveness of a smoking cessation program based on "impediment profiling," the elucidation of an individual participant's personal barriers, with provision of tailored interventions accordingly.

Methods: A literature search was conducted to identify established impediments to smoking cessation. A long impediment profiler (LIP) was developed from validated survey instruments and used as a screening tool to identify individuals' barriers to quitting.

Multiple determinants contribute to the virulence of HSV ocular and CNS infection and identification of serine 34 of the US1 gene as an ocular disease determinant.

Purpose: The virulence of any given strain of herpes simplex virus (HSV) is probably due to the effects of the constellation of genes in that strain and how they act in concert to promote disease. The goal of this work was to develop a system to identify and study the role of multiple genes in HSV disease.

Methods: Mixed ocular infection with HSV-1 strains CJ394 and OD4 yield recombinants with increased ocular and central nervous system (CNS) virulence.